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Details for anatomical structure: acidophil mammotroph cell of anterior pituitary

EndoNet ID: ENC00001

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Synonyms

acidophil mammotroph cell of anterior pituitary, chromophil cell, Endocrinocytus acidophilus

General information

secreting prolactin

Links to other resources

Cytomer cy0011196

Larger structures

  • brain
  • pituitary_gland_of_diencephalon
  • adenohypophysis
  • central_nerve_system_element

Substructures

    Secreted hormones

    • Hormone: angiotensin II

      • Nonclassical Anterior Pituitary Substances:Peptides [1]

    • Hormone: galanin

      • Nonclassical Anterior Pituitary Substances:Peptides [1]

    • Hormone: TRH

      • Nonclassical Anterior Pituitary Substances: Peptides [1]

    • Hormone: VIP

    • Hormone: PRL

      Influenced by:

      • dopamine receptor D2
        in acidophil_mammotroph_cell_of_anterior_pituitary
      • TRH-R
        in acidophil_mammotroph_cell_of_anterior_pituitary
      • CXCR1
        in acidophil_mammotroph_cell_of_anterior_pituitary
        • CINC/ stimulates PRL secretion from anterior pituitary monolayer cultures in a concentration-dependent manner with a substantioal lag time. [3]
      • GHS-R1
        in pituitary_gland_of_diencephalon
        • ...stimulatory effect of CST on PRL release is exerted through a receptor not shared by SST...it has been reported that CST(...)binds with high affinity to GHS-R1a(...) which in turn is known to stimulate PRL secretion [4]

    Receptors

    • Receptor: dopamine receptor D2

      Induced phenotype:

      • Hyperprolactinemia
        • Hyperprolactinaemia is common in patients with hypopituitarism, due to the interference of a pituitary mass with dopaminergic inhibition of prolactin secretion. [5]

      Influences:

      • PRL

    • Receptor: TRH-R

      Influences:

      • PRL

    • Receptor: CXCR1

      Influences:

      • PRL
        • CINC/ stimulates PRL secretion from anterior pituitary monolayer cultures in a concentration-dependent manner with a substantioal lag time. [3]
    Reference