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Details for anatomical structure: supra-optic nucleus

EndoNet ID: ENC00026

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supra-optic nucleus, supraoptic nucleus of hypothalamus, Nucleus supraopticus

General information

A small nucleus of closely packed neurons that overlies the optic chiasma and is intimately connected with the neurohypophysis

Links to other resources

Cytomer cy0001663

Larger structures


      Secreted hormones

      • Hormone: Oxytocin-Neurophysin 1

      • Hormone: antidiuretic hormone

        • Is stored in the neurohypophysis. [1]
        • Expression of vasopressin (VP) mRNA in the human supraoptic nuclei. [2]

        Influenced by:

        • thyroid hormone receptor beta 2
          in paraventricular_nucleus_of_hypothalamus
          • TRH is colocalized with vasopressin in the supraoptic and paraventricular nuclei and can participate in the regulation og biosynthesis and secretion of vasopressin [3]
          • TRH stimulates vasopressin biosynthesis in young rats [3]
      • Hormone: galanin-like peptide Isoform 1

      • Hormone: secretin


      • Receptor: galanin receptor 2