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Details for anatomical structure: supra-optic nucleus

EndoNet ID: ENC00026

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Synonyms

supra-optic nucleus, supraoptic nucleus of hypothalamus, Nucleus supraopticus

General information

A small nucleus of closely packed neurons that overlies the optic chiasma and is intimately connected with the neurohypophysis

Links to other resources

Cytomer cy0001663

Larger structures

  • brain
  • hypothalamus
  • central_nerve_system_element

Substructures

  • glial_cell_of_central_nervous_system
  • astrocyte
  • microglial_cell_in_central_nervous_system
  • oligodendrocyte
  • bergmann_glia

Secreted hormones

  • Hormone: Oxytocin-Neurophysin 1

  • Hormone: antidiuretic hormone

    • Is stored in the neurohypophysis. [1]
    • Expression of vasopressin (VP) mRNA in the human supraoptic nuclei. [2]

    Influenced by:

    • thyroid hormone receptor beta 2
      in paraventricular_nucleus_of_hypothalamus
      • TRH is colocalized with vasopressin in the supraoptic and paraventricular nuclei and can participate in the regulation og biosynthesis and secretion of vasopressin [3]
      • TRH stimulates vasopressin biosynthesis in young rats [3]

  • Hormone: galanin-like peptide Isoform 1

  • Hormone: secretin

Receptors

  • Receptor: galanin receptor 2

Reference