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Details for anatomical structure: corpus luteum

EndoNet ID: ENC00031

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Synonyms

corpus luteum, luteal corpus, yellow body of ovary, Corpus luteum

General information

The yellow endocrine body, 1 to 1,,5 cm in diameter, formed in the ovary at the site of a ruptured ovarian follicle immediately after ovulation; there is an early stage of proliferation and vascularization before full maturity; later, there is a festooned and bright yellowish lutein zone traversed by trabeculae of theca interna containing numerous blood vessels; the corpus luteum secretes oestrogen, as did the follicle, and also progesterone

Links to other resources

Cytomer cy0020813

Larger structures

    Substructures

      Secreted hormones

      • Hormone: progesterone

      • Hormone: inhibin B

      • Hormone: VEGF-165

        • The luteal tissue is the major site of Ang II, ACE, AT1R, and VEGF. [1]

      Receptors

      • Receptor: PRLR

      • Receptor: Lysophosphatidic acid receptor 2

        Induced phenotype:

        • negative regulation of progesterone biosynthetic process
          • In luteal cells temporally coexpressing endogenous LPA2 receptor during mid-cycle, LPA inhibits agonist-stimulated progesterone production at a step distal to the cyclic AMP formation and before the steroid synthesis in mitochondria. [2]
      Reference