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Synonyms
nerve, , Nervus
General information
A whitish cordlike structure composed of one or more bundles of myelinated or unmyelinated nerve fibers (or mixtures of both); coursing outside of the central nervous system
CNTF mRNA is widely expressed in the brain, heart, lung, liver, kidney and testis of the rat, in addition to preferential expression in the sciatic nerve. [1]
Stimulation of the CB1 receptor results in the inhibition of a range of excitatory and inhibitory neurotransmitters, like acetylcholine, noradrenaline, dopamine, 5-hydroxytryptamine, D-aspartate and cholecystokinin. [2]
Furthermore, Lpar1-deficient mice are resistant to neuropathic pain induced by partial sciatic nerve ligation. [3]
It was shown that LPA is able to initiate neuropathic pain in the peripheral nervous system, which occurs through the activation of LPA1 and subsequent release of the pronociceptive factor substance P. [4]