Details for anatomical structure: smooth muscle
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- Related structures
- Hormones
- Receptors
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- Top
- Related structures
- Hormones
- Receptors
-
Click to access the toolbox
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Synonyms
smooth muscle, ,Links to other resources
Cytomer | cy0041805 |
Related structures
Larger structures
Substructures
Secreted hormones
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Hormone: pentraxin 3
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Hormone: PDGFD
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Hormone: eotaxin
- Human eotaxin is an 8,3-kDa, 74-amino-acid residue, nonglycosylated polypeptide secreted by endothelial cells, fibroblasts, macrophages, ciliated and nonciliated bronchial epithelial cells, smooth muscle cells, chondrocytes, and eosinophils. [3]
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Hormone: galectin-1
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Hormone: galectin-1
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Hormone: EGF
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Hormone: FGF-1 isoform 1
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Hormone: VCAM1 soluble form
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Hormone: 20-HETE
Receptors
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Receptor: NPY5-R
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Receptor: PPARgamma1
- The peroxisome proliferation-activated receptor gamma (PPARγ)1 is a member of the nuclear receptor superfamily. It is expressed in many cell types, including adipocytes, epithelial cells, B- and T-cells, macrophages, endothelial cells, neutrophils, and smooth muscle cells [4]
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Receptor: ER-beta
Induced phenotype:
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Receptor: T-cadherin
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Receptor: CysLTR2
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Receptor: TNFRSF12A
Induced phenotype:
- positive regulation of smooth muscle proliferation
- TNFSF12 induces proliferation of human aortic smooth muscle cells in vitro. [6]
- positive regulation of smooth muscle proliferation
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Receptor: CCK-2
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Receptor: TrpV4-A
Induced phenotype:
- positive regulation of smooth muscle contraction
- Functional TRPV4 is expressed in human airway smooth muscle cells and may act as an osmolarity sensor in the airway. [7]
- Activation of TRPV4 on airway smooth muscle cells increases intracellular Ca2+ level, which may induce smooth muscle contraction. [7]
- TRPV4 is the most plausible channel involved in hypotonic stimulation-induced airway contraction. [7]
- positive regulation of smooth muscle contraction
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Receptor: Vascular endothelial growth factor receptor 1
- These findings demonstrate that vascular SMCs express functional flt-1 receptors after arterial injury. [8]
Induced phenotype:
- vessel maturation
- PlGF also acts on VEGFR-1-expressing smooth muscle cells, thus promoting vessel maturation. [9]