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Details for anatomical structure: stomach

EndoNet ID: ENC00132

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Synonyms

stomach, gaster, Gaster

General information

A large irregularly piriform sac between the oesophagus and the small intestine, the most dilated portion of the digestive tube, lying just beneath the diaphragm; it has a capacity of about 1 liter

Links to other resources

Cytomer cy0047748

Larger structures

    Substructures

      Secreted hormones

      • Hormone: ghrelin

        Influenced by:

        • GL-R
          in stomach
          • These results suggest that glucagon stimulates acute release of both forms of ghrelin and thereafter upregulates synthesis and release of desacyl-ghrelin in the rat stomach. [1]
      • Hormone: lipocalin 2

        • NGAL was found in a variety of normal and pathological human tissues (cell type-specific pattern of expression in bronchus, stomach, small intestine, pancreas, kidney, prostate gland, and thymus). [2]
      • Hormone: TFF1

        • Found in stomach [3]
      • Hormone: TFF2

      • Hormone: MIP-3 beta

      • Hormone: hepcidin

      • Hormone: BCA-1

      • Hormone: MCP-4

      • Hormone: AGR2

      • Hormone: Cystatin-C

      • Hormone: NPW23

      • Hormone: NPW30

      • Hormone: REG1A

      • Hormone: IL-17B

      • Hormone: FGF-23

      • Hormone: GRP

        Influenced by:

        • GRP-R
          in stomach
          • Stimulation of gastrin release from antral G-cells [4]

      Receptors

      • Receptor: GL-R

        Influences:

        • ghrelin
          • These results suggest that glucagon stimulates acute release of both forms of ghrelin and thereafter upregulates synthesis and release of desacyl-ghrelin in the rat stomach. [1]
      • Receptor: sst1

      • Receptor: sst2

      • Receptor: sst5

      • Receptor: sst3

      • Receptor: sst4

      • Receptor: TLR7

      • Receptor: glucagon-like peptide 2 receptor

      • Receptor: frizzled 3

      • Receptor: GRP-R

        Influences:

        • GRP
          • Stimulation of gastrin release from antral G-cells [4]
      • Receptor: hepatocyte growth factor receptor

      • Receptor: CRF-R1

      • Receptor: CRF-R2

      • Receptor: neurotensin receptor type 1

        Induced phenotype:

        • decrease in gastric acid secretion
      • Receptor: PRLR

      • Receptor: Lysophosphatidic acid receptor 1

      • Receptor: Lysophosphatidic acid receptor 5

      • Receptor: Lysophosphatidic acid receptor 2

      • Receptor: Sphingosine 1-phosphate receptor 2

      • Receptor: 5-HT-2B

        Induced phenotype:

        • gastro-intestinal system smooth muscle contraction
          • 5-HT 2B receptors are found peripherally in the stomach fundus and contraction of the rat stomach fundus via these receptors has been elicited. [5]
      • Receptor: CCK-1

        Induced phenotype:

        • inhibition of gastric emptying
          • In humans strong evidence suggests CCK1R activation is involved in the regulation of numerous physiological processes, including inhibition of gastric emptying. [6]
      Reference