Details for anatomical structure: substantia nigra

Related structures
Hormones
Receptors
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EndoNet ID: ENC00134

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Synonyms

substantia nigra, nucleus of basis pedunculi, Soemmering's substance, Substantia nigra

General information

A large cell mass, crescentic on transverse section, extending forward over the dorsal surface of the crus cerebri from the rostral border of the pons into the subthalamic region

Links to other resources

Cytomer

cy0006113

Larger structures

Substructures

Secreted hormones

Hormone: NPB23
Hormone: NPB29

Receptors

Receptor: dopamine receptor D2
Receptor: frizzled 10
Receptor: NPY2-R
Receptor: EAAT3
Receptor: CRF-R1
Receptor: 5-HT-2C
- The location of 5-HT-2C recpetors is on postsynaptic sites of the substantia nigra. [1]
Influences:
- GABA
  
  The selective activation of 5-HT2C receptors stimulates non-DA neurons in the substantia nigra pars reticulata (SNr) and mediate an increase in GABA extracellular levels in the SNr. [2]
Receptor: 5-hydroxytryptamine receptor 4
Induced phenotype:
- optpkinetic behavior
  
  The expression of the 5-HT 4 receptors in the basal ganglia and substantia nigra indicates a role in the control of visuo-motor activity. [3]
Receptor: OPRL1

Reference

EndoNet

The information resource about the endocrine network in human.

Details for anatomical structure: substantia nigra

Synonyms

General information

Links to other resources

Related structures

Larger structures

Substructures

Secreted hormones

Hormone: NPB23 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_0_toolsBtn',{id:'j_idt91:0:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_0_j_idt99',{id:'j_idt91:0:j_idt99',target:'j_idt91:0:toolsBtn',dynamic:true});});

Hormone: NPB29 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_1_toolsBtn',{id:'j_idt91:1:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_1_j_idt99',{id:'j_idt91:1:j_idt99',target:'j_idt91:1:toolsBtn',dynamic:true});});

Receptors

Receptor: dopamine receptor D2 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt139_0_toolsBtn',{id:'j_idt139:0:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt139_0_j_idt145',{id:'j_idt139:0:j_idt145',target:'j_idt139:0:toolsBtn',dynamic:true});});

Receptor: frizzled 10 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt139_1_toolsBtn',{id:'j_idt139:1:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt139_1_j_idt145',{id:'j_idt139:1:j_idt145',target:'j_idt139:1:toolsBtn',dynamic:true});});

Receptor: NPY2-R ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt139_2_toolsBtn',{id:'j_idt139:2:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt139_2_j_idt145',{id:'j_idt139:2:j_idt145',target:'j_idt139:2:toolsBtn',dynamic:true});});

Receptor: EAAT3 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt139_3_toolsBtn',{id:'j_idt139:3:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt139_3_j_idt145',{id:'j_idt139:3:j_idt145',target:'j_idt139:3:toolsBtn',dynamic:true});});

Receptor: CRF-R1 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt139_4_toolsBtn',{id:'j_idt139:4:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt139_4_j_idt145',{id:'j_idt139:4:j_idt145',target:'j_idt139:4:toolsBtn',dynamic:true});});

Receptor: 5-HT-2C ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt139_5_toolsBtn',{id:'j_idt139:5:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt139_5_j_idt145',{id:'j_idt139:5:j_idt145',target:'j_idt139:5:toolsBtn',dynamic:true});});

Influences:

Receptor: 5-hydroxytryptamine receptor 4 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt139_6_toolsBtn',{id:'j_idt139:6:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt139_6_j_idt145',{id:'j_idt139:6:j_idt145',target:'j_idt139:6:toolsBtn',dynamic:true});});

Induced phenotype:

Receptor: OPRL1 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt139_7_toolsBtn',{id:'j_idt139:7:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt139_7_j_idt145',{id:'j_idt139:7:j_idt145',target:'j_idt139:7:toolsBtn',dynamic:true});});

Hormone: NPB23

Hormone: NPB29

Receptor: dopamine receptor D2

Receptor: frizzled 10

Receptor: NPY2-R

Receptor: EAAT3

Receptor: CRF-R1

Receptor: 5-HT-2C

Receptor: 5-hydroxytryptamine receptor 4

Receptor: OPRL1