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Details for anatomical structure: corpus luteum

EndoNet ID: ENC00166

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corpus luteum, luteal corpus, yellow body of ovary, Corpus luteum

General information

The yellow endocrine body, 1 to 1,,5 cm in diameter, formed in the ovary at the site of a ruptured ovarian follicle immediately after ovulation; there is an early stage of proliferation and vascularization before full maturity; later, there is a festooned and bright yellowish lutein zone traversed by trabeculae of theca interna containing numerous blood vessels; the corpus luteum secretes oestrogen, as did the follicle, and also progesterone

Links to other resources

Cytomer cy0020813

Larger structures


      Secreted hormones

      • Hormone: progesterone

      • Hormone: angiotensin II

      • Hormone: Oxytocin-Neurophysin 1

        • However, OT is also synthesized in peripheral tissues, e.g. uterus, placeta, amnion, corpus luteum, testis and heart. [1]


      • Receptor: progesterone receptor

      • Receptor: PRLR

      • Receptor: ER-beta

        Induced phenotype:

        • vasculogenesis
          • The corpus luteum is associated with angiogenesis followed by vascular regression. As estradiol is produced by granulosa-lutein cells of the corpus luteum, with receptors on endothelial cells, it may have potential effects on endothelial cell function. It is not known whether estradiol has any direct effects, but it is notable that molecules based on estrogen have been shown to have anti-angiogenic properties. Therfore, estradiol may have effects on the luteal vasculature. [2]
      • Receptor: angiotensin II type 1 receptor