Details for anatomical structure: basophil corticotroph cell of anterior pituitary
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- General information
- Related structures
- Hormones
- Receptors
-
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- Top
- General information
- Related structures
- Hormones
- Receptors
-
Click to access the toolbox
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Synonyms
basophil corticotroph cell of anterior pituitary, chromophil cell, Endocrinocytus basophilusGeneral information
secreting adrenocorticotropic hormoneLinks to other resources
Cytomer | cy0011197 |
Related structures
Larger structures
Substructures
Secreted hormones
-
Hormone: ACTH
- The action of CRH on ACTH release is strongly potentiated by vasopressin, that is co-produced in increasing amounts when the hypothalamic paraventricular neurons are chronically activated. [1]
- Vasopressin stimulates ACTH release in humans, oxytocin inhibits it. [1]
- [2]
- Pituitary corticotropic cells express a specific vasopressin receptor, called V1b or V3, through which vasopressin stimulates corticotropin secretion. [3]
Influenced by:
- insulin receptor in basophil_corticotroph_cell_of_anterior_pituitary
- V1b
in
basophil_corticotroph_cell_of_anterior_pituitary
- Vasopressin is an important regulator of pituitary adrenocorticotropin (ACTH) secretion, mainly by potentiating the stimulatory effect of corticotropin releasing hormone. [4]
- Effect of vasopressin in the pituitary corticotrope cells are mediated by the vasopressin type 1b receptor subtype, which is coupled to phospholipase C, leading to increases in cytosolic calcium and activation of protein kinase C. [4]
- CXCR1
in
basophil_corticotroph_cell_of_anterior_pituitary
- CINC/gro stimulates ACTH secretion from anterior pituitary monolayer cultures with a substantial lag time. [5]
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Hormone: MSH
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Hormone: lipotropin beta
Influenced by:
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Hormone: lipotropin gamma
-
Hormone: β-endorphin
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Hormone: angiotensin II
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Hormone: CLIP
Receptors
-
Receptor: V1b
Influences:
- ACTH
- Vasopressin is an important regulator of pituitary adrenocorticotropin (ACTH) secretion, mainly by potentiating the stimulatory effect of corticotropin releasing hormone. [4]
- Effect of vasopressin in the pituitary corticotrope cells are mediated by the vasopressin type 1b receptor subtype, which is coupled to phospholipase C, leading to increases in cytosolic calcium and activation of protein kinase C. [4]
- ACTH
-
Receptor: insulin receptor
Induced phenotype:
- tertiary adrenal insufficiency
- Tertiary adrenal insufficiency is the result of a hypothalamic disease and thereby a decrease in corticotropin releasing factor. [7]
Influences:
- tertiary adrenal insufficiency
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Receptor: orexin receptor 2
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Receptor: CXCR1
Influences: