Status
Please wait ...

Details for anatomical structure: D cell

EndoNet ID: ENC00179

To link to the content of EndoNet use the EndoNet ID that is given on the detail pages in the format ENX0000, where X is a place holder for the type of the component (e. g. R for receptor or C for anatomical structure).
As URL for the linking append this ID to the detail page for this type of component.
For an hormone that would be: 

http://endonet.bioinf.med.uni-goettingen.de/hormone/ENH00000

It is also possible to use the search of EndoNet to link to the right detail page. The URL should look like 

http://endonet.bioinf.med.uni-goettingen.de/search/ENC00000
If the search pattern is unambigious the user is directed to the corresponding detail page.

Synonyms

D cell, delta cell,

General information

produces somatostatin; somatostatin inhibits insulin and glucagon secretion

Links to other resources

Cytomer cy0044733

Larger structures

  • parts_of_human_body
  • digestive_system
  • pancreas
  • pancreatic_islets

Substructures

    Secreted hormones

    • Hormone: gastrin

      • Co-localization of gastrin and CRH in D-cells was determined by immunocytochemistry. S.456 [1]

    • Hormone: CRH

    • Hormone: somatostatin

      • SST also inhibits pancreatic polypeptide as well as endogenous SST secretion from delta-cells through an autofeedback mechanism. [2]

      Influenced by:

      • sst2
        in D_cell
      • sst3
        in D_cell
      • sst1
        in D_cell
      • sst5
        in D_cell
      • CCK-1
        in D_cell
        • The CCK1 receptor mRNA and protein have been localized in the human gastric mucosa within D cells, where CCK can stimulate somatostatin secretion. [3]

    Receptors

    • Receptor: sst5

      Influences:

      • somatostatin

    • Receptor: sst1

      Influences:

      • somatostatin

    • Receptor: sst2

      Influences:

      • somatostatin

    • Receptor: sst3

      Influences:

      • somatostatin

    • Receptor: CCK-1

      • The CCK1 receptor mRNA and protein have been localized in the human gastric mucosa within D cells. [3]

      Influences:

      • somatostatin
        • The CCK1 receptor mRNA and protein have been localized in the human gastric mucosa within D cells, where CCK can stimulate somatostatin secretion. [3]
    Reference