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Details for anatomical structure: amygdaloid body

EndoNet ID: ENC00182

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Synonyms

amygdaloid body, amygdaloid complex, amygdala, amygdaloid nuclear complex, amygdaloid nuclear groups, amygdaloid nucleus, archistriatum, Corpus amygdaloideum

General information

A rounded mass of gray matter in the temporal lobe internal to the cortex of the uncus and immediately anterior to the inferior horn of the lateral ventricle; its major afferents are olfactory and its efferent connections are with the hypothalamus and mediodorsal nucleus of the thalamus and it is also reciprocally associated with the cortex of the temporal lobe

Links to other resources

Cytomer cy0014736

Larger structures

    Substructures

      Secreted hormones

      • Hormone: CGRP1

      • Hormone: PAI-2

      • Hormone: GABA

        Influenced by:

        • 5-HT3 receptor
          in amygdaloid_body
          • Activation of presynaptic 5-HT-3 receptors facilitate synaptic GABA release from GABAergic presynaptic nerve terminals in the amygdala. [1]
        • 5-HT-1A
          in amygdaloid_body
          • Activated 5-HT-1A receptors inhibite GABA release in the basolateral amygdala. [2]

      Receptors

      • Receptor: NPY5-R

      • Receptor: CRF-R1

      • Receptor: 5-hydroxytryptamine receptor 4

      • Receptor: NPY2-R

      • Receptor: GPR7

      • Receptor: 5-HT3 receptor

        • Activation of presynaptic 5-HT-3 receptors facilitate synaptic GABA release from GABAergic presynaptic nerve terminals in the amygdala. [1]

        Influences:

        • GABA
          • Activation of presynaptic 5-HT-3 receptors facilitate synaptic GABA release from GABAergic presynaptic nerve terminals in the amygdala. [1]
      • Receptor: Lysophosphatidic acid receptor 3

      • Receptor: GRP-R

      • Receptor: 5-HT-1A

        • Activated 5-HT-1A receptors inhibite GABA release in the basolateral amygdala. [2]

        Influences:

        • GABA
          • Activated 5-HT-1A receptors inhibite GABA release in the basolateral amygdala. [2]
      • Receptor: dopamine receptor D4

      • Receptor: OPRL1

      • Receptor: NPSR1

        • NPS receptor mRNA is widely distributed and most abundant in the amygdala, thalamus, hypothalamus, and cortex. [3]

        Induced phenotype:

        • attenuation of anxiety behavior
          • NPS Attenuates Anxiety-like Behavior [4]
      Reference