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Details for anatomical structure: eosinophil granulocyte

EndoNet ID: ENC00219

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Synonyms

eosinophil granulocyte, polymorphonuclear eosinophil leukocyte, eosinophilic leukocyte, Granulocytus acidophilieus (eosinophilicus)

General information

granulocytic leukocyte with a two-lobed nucleus; contains eosinophilic granules and lysosomal enzymes; is involved in the destruction of parasites, especially in worm infestation, and shows diurnal variation in number; only little phagocytic

Links to other resources

Cytomer cy0049461

Larger structures

    Substructures

      Secreted hormones

      • Hormone: ENA-78

      • Hormone: IL-3

      • Hormone: CCL28

      • Hormone: eotaxin

        • Human eotaxin is an 8,3-kDa, 74-amino-acid residue, nonglycosylated polypeptide secreted by endothelial cells, fibroblasts, macrophages, ciliated and nonciliated bronchial epithelial cells, smooth muscle cells, chondrocytes, and eosinophils. [1]
      • Hormone: PAF

      Receptors

      • Receptor: glucocorticoid receptor

      • Receptor: GR-beta

      • Receptor: IgE Fc receptor gamma-subunit

      • Receptor: H3

      • Receptor: H2

      • Receptor: histamine H4 receptor

      • Receptor: CSF2RB

      • Receptor: IL-5R

      • Receptor: IL-5Ralpha

      • Receptor: CCR3

      • Receptor: SIGLEC-7

      • Receptor: oxoeicosanoid receptor 1

      • Receptor: Sphingosine 1-phosphate receptor 1

      • Receptor: Sphingosine 1-phosphate receptor 2

      • Receptor: Sphingosine 1-phosphate receptor 3

      Reference