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Details for anatomical structure: bronchi

EndoNet ID: ENC00234

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Synonyms

bronchi, , Bronchi

General information

Any of the larger subdivisions of the trachea, serving to convey air to and from the lungs; having an outer fibrous coat with irregularly placed plates of hyaline cartilage, an interlacing network of smooth muscle and a mucous membrane of columnar ciliated epithelial cells

Links to other resources

Cytomer cy0049599

Larger structures

  • parts_of_human_body
  • lung

Substructures

  • epithelial_cell_with_microvilli
  • propria_mucosa_of_bronchus
  • cell:plasma_cell
  • neutrophil_granulocyte
  • chondroblast
  • muscularis_of_bronchus
  • smooth_muscle_cell
  • eosinophil_granulocyte
  • lymphocyte
  • bronchial_epithelial_cell
  • mast_cell
  • mesenchyme_cell
  • basophil_granulocyte
  • macrophage
  • fibroblast

Secreted hormones

  • Hormone: lipocalin 2

    • NGAL was found in a variety of normal and pathological human tissues (cell type-specific pattern of expression in bronchus, stomach, small intestine, pancreas, kidney, prostate gland, and thymus). [1]
  • Hormone: C-C motif chemokine 2

  • Hormone: IL-8

    • The bronchial epithelium is a source not only for the C-X-C chemokines interleukin-8 and GRO-alpha, but also for the neutrophil chemoattractant granulocyte chemotactic protein (GCP)-2. [2]

    Influenced by:

    • IL-17R
      in bronchi
      • Compared to baseline (inherent) release, the peak response of interleukin-17-induced release of interleukin-8 was 225% (+/- 13%). [2]
  • Hormone: GROalpha

    • The bronchial epithelium is a source not only for the C-X-C chemokines interleukin-8 and GRO-alpha, but also for the neutrophil chemoattractant granulocyte chemotactic protein (GCP)-2. [2]

    Influenced by:

    • IL-17R
      in bronchi
      • Compared to baseline (inherent) release, the peak response of interleukin-17-induced release of GRO-alpha was 259% (+/-12%). [2]
  • Hormone: mucin-2

  • Hormone: soluble PSGL-1

Receptors

  • Receptor: IL-17R

    Influences:

    • IL-8
      • Compared to baseline (inherent) release, the peak response of interleukin-17-induced release of interleukin-8 was 225% (+/- 13%). [2]
    • GROalpha
      • Compared to baseline (inherent) release, the peak response of interleukin-17-induced release of GRO-alpha was 259% (+/-12%). [2]
Reference