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Details for anatomical structure: cerebellum

EndoNet ID: ENC00262

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Synonyms

cerebellum, epencephalon-1, Cerebellum

General information

The large posterior brain mass lying dorsal to the pons and medulla and ventral to the posterior portion of the cerebrum; it consists of two lateral hemispheres united by a narrow middle portion, the vermis.

Links to other resources

Cytomer cy0048118

Larger structures

  • brain
  • circulatory_system__hematopoietic_system
  • central_nerve_system_element

Substructures

  • glial_cell_of_central_nervous_system
  • astrocyte
  • microglial_cell_in_central_nervous_system
  • oligodendrocyte
  • granular_layer_of_cerebellar_cortex
  • Purkinje_cell
  • neuron
  • basket_cell
  • cerebellar_cortex
  • Golgi_cell
  • bergmann_glia

Secreted hormones

  • Hormone: neuregulin-2

  • Hormone: MCH

  • Hormone: chordin

  • Hormone: QRFP

  • Hormone: persephin

  • Hormone: FGF-20

  • Hormone: ADNP

  • Hormone: FGF-2

  • Hormone: frataxin, mitochondrial

  • Hormone: TIP39

  • Hormone: GABA

    Influenced by:

    • CB1
      in basket_cell
    • CB1
      in cerebellum

  • Hormone: glutamate

    Influenced by:

    • CB1
      in cerebellum

  • Hormone: CGRP1

  • Hormone: Wnt-3

  • Hormone: galectin-1

  • Hormone: angiopoietin-like protein 4

Receptors

  • Receptor: mineralcorticoid receptor

  • Receptor: frizzled 3

  • Receptor: frizzled 10

  • Receptor: GPR7

  • Receptor: frizzled 2

    Induced phenotype:

    • accumulation of intracellular Ca2+ concentration
      • The Fzd2 receptor promotes the accumulation of intracellular Ca concentration. [1]
      • Traumatic brain injury can stimulate activation of the Wnt5a/Fzd2 signaling pathway [1]
      • Activated Wnt5a/Fzd2 signaling plays an important role in calcium overloading process within cells post traumatic brain injury. [1]

  • Receptor: NMU-R1

  • Receptor: GPR54

  • Receptor: mGluR4

  • Receptor: Secretin receptor

    • The existence of secretin and secretin receptor in the cerebellum was confirmed by others using an immunohistochemical and an in vitro autoradiographic approach. [2]

  • Receptor: CB1

    Influences:

    • GABA
    • glutamate

  • Receptor: 5-ht-5 receptor

Reference