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Details for anatomical structure: Purkinje cell

EndoNet ID: ENC00265

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Synonyms

Purkinje cell, , Neuron piriforme (purkinjiense)

General information

Found in the Purkinje cell layer of cerebellar cortex

Links to other resources

Cytomer cy0011416

Larger structures

    Substructures

      Secreted hormones

      • Hormone: NRG-1

      • Hormone: noggin

      • Hormone: GABA

        Influenced by:

        • CB1
          in hippocampus
      • Hormone: Granulin-1

      • Hormone: FAM3B-b

      Receptors

      • Receptor: alpha 1A-adrenoreceptor

        Induced phenotype:

        • regulation of inhibitory postsynaptic membrane potential
          • Alpha 1A ARs may play a role in the timing and receipt of the inhibitory signals from Purkinje cells. [1]
      • Receptor: alpha 1B-adrenoreceptor

        Induced phenotype:

        • regulation of inhibitory postsynaptic membrane potential
          • Alpha 1B ARs may play a role in the timing and receipt of the inhibitory signals from Purkinje cells. [1]
      • Receptor: alpha 1D-adrenoreceptor

      • Receptor: alpha-2A adrenoreceptor

        Induced phenotype:

        • regulation of inhibitory postsynaptic membrane potential
          • Alpha 2 AR subtypes are expressed in the cerebellar cortex including Purkinje cells and may play a role in motor coordination. Presynaptic activation of alpha 2-ARs inhibits cerebellar inhibitory synaptic transmission and therefore negatively regulates inhibitory postsynaptic membrane potential. [2]
      • Receptor: alpha-2B adrenoreceptor

        Induced phenotype:

        • regulation of inhibitory postsynaptic membrane potential
          • Alpha 2 AR subtypes are expressed in the cerebellar cortex including Purkinje cells and may play a role in motor coordination. Presynaptic activation of alpha 2-ARs inhibits cerebellar inhibitory synaptic transmission and therefore negatively regulates inhibitory postsynaptic membrane potential. [2]
      • Receptor: alpha-2C adrenoreceptor

        Induced phenotype:

        • regulation of inhibitory postsynaptic membrane potential
          • Alpha 2 AR subtypes are expressed in the cerebellar cortex including Purkinje cells and may play a role in motor coordination. Presynaptic activation of alpha 2-ARs inhibits cerebellar inhibitory synaptic transmission and therefore negatively regulates inhibitory postsynaptic membrane potential. [2]
      • Receptor: 5-ht-5 receptor

      • Receptor: GABAA receptor

      • Receptor: GluR-2

      • Receptor: GluR-4

      • Receptor: GluR-1

      • Receptor: EAAT4

        Induced phenotype:

        • glutamate transport
          • EAAT4 controls the transport of glutamate by different anion fluxes. [3]
      Reference