Details for anatomical structure: killer cell
- Top
- General information
- Related structures
- Hormones
- Receptors
-
Click to access the toolbox
- Top
- General information
- Related structures
- Hormones
- Receptors
-
Click to access the toolbox
To link to the content of EndoNet use the EndoNet ID that is given on the detail
pages in the format ENX0000, where X is a place holder for the type of
the component (e. g. R for receptor or C for anatomical structure).
As URL
for the linking append this ID to the detail page for this type of component.
For an hormone that would be:
http://endonet.bioinf.med.uni-goettingen.de/hormone/ENH00000
It is also possible to use the search of EndoNet to link to the right detail page. The URL should look like
http://endonet.bioinf.med.uni-goettingen.de/search/ENC00000If the search pattern is unambigious the user is directed to the corresponding detail page.
Synonyms
killer cell, null-cell, LymphocytusGeneral information
Cellular cytotoxicityLinks to other resources
Cytomer | cy0045844 |
Related structures
Larger structures
Substructures
Secreted hormones
-
Hormone: IFN-gamma
Influenced by:
- IL-18R1 in killer_cell
- CD72
in
dendritic_cell_in_lymphoid_tissues
- Activated NK cells express CD100 and produce soluble CD100. They interact with dendritic cells by several routs among which is the CD100-CD72 interaction. Such interaction lead to IFNgamma secretion which in turn activates other cells of the immune system. [1]
- CD72
in
macrophage
- Activated NK cells express CD100 and produce soluble CD100. They interact with macrophages by several routs among which is the CD100-CD72 interaction. Such interaction lead to IFNgamma secretion which in turn activates other cells of the immune system. [1]
-
Hormone: IL-22
-
Hormone: SEMA4D
- IL-2 activated NK cells secrete soluble CD100. [1]
Influenced by:
- CD72
in
dendritic_cell_in_lymphoid_tissues
- Activated NK cells express CD100 and produce soluble CD100. They interact with dentritic cells by several routs among which is the CD100-CD72 interaction. Such interaction lead to soluble CD100 secretion which in turn activates other cells of the immune system. [1]
- CD72
in
macrophage
- Activated NK cells express CD100 and produce soluble CD100. They interact with macrophages by several routs among which is the CD100-CD72 interaction. Such interaction lead to soluble CD100 secretion which in turn activates other cells of the immune system. [1]
Receptors
-
Receptor: IL-12beta2R
-
Receptor: IL-18Rbeta
-
Receptor: IgE Fc receptor gamma-subunit
-
Receptor: SIGLEC-7
-
Receptor: IL-8R B
-
Receptor: CXCR1
-
Receptor: CXCR3
-
Receptor: CXCR5
-
Receptor: CXCR4
-
Receptor: CX3CR1
-
Receptor: CD160 antigen
-
Receptor: LIR-1
-
Receptor: CD7
-
Receptor: IL-18R1
Influences:
-
Receptor: hLAIR1-1
-
Receptor: Sphingosine 1-phosphate receptor 5
Induced phenotype:
- positive regulation of leukocyte migration
- NK cells rely on S1PR5 to attain a normal tissue distribution, which might also function to promote egress from the bone marrow and lymph nodes into the vascular compartments in response to S1P gradients. [2]
- positive regulation of leukocyte migration