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Details for anatomical structure: osteocyte

EndoNet ID: ENC00325

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Synonyms

osteocyte, osseous cell, bone cell, bone corpuscle, Osteocytus

General information

major cell type of mature bone; maintaining the bone matrix;

Links to other resources

Cytomer cy0011282

Larger structures

    Substructures

      Secreted hormones

      • Hormone: osteocalcin

      • Hormone: bone sialoprotein 2

      • Hormone: sclerostin

      Receptors

      • Receptor: ER-beta

        Induced phenotype:

        • detection of mechanical stimulus
          • Membrane associated estrogen receptors are essential for the transduction of mecahnical forces into intracellular survival signaling in osteocytes and osteoblast, independent of ligand binding. [1]
      • Receptor: CaSR

        Induced phenotype:

        • bone cell metabolism
          • The CaSR regulates the recruitment, differentiation and survival of osteoblast and osteoclasts. [2]
      Reference