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Details for anatomical structure: ileum

EndoNet ID: ENC00405

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Synonyms

ileum, , Ileum

General information

The lowest three fifths of the small intestine, about 12 feet in length, extending from the junction with the jejunum to the ileocecal opening; it is distinct from jejunum in being typically smaller in diameter with thinner walls, having smaller and less complex plicae circulares; its mesentery having more fat and its arteries forming more tiers of arterial arcades with shorter vasa recta

Links to other resources

Cytomer cy0032172

Larger structures

    Substructures

      Secreted hormones

      • Hormone: GRP

        • GRP is expressed in submucosal cells of the ileum. [1]
      • Hormone: NT

        • Protein kinase D (PKD) family members (PKD1, 2, and 3) have been identified as important regulators of secretory transport at the trans-Golgi network: PKD1 contributes to stimulated NT secretion. [2]

      Receptors

      • Receptor: NPY4-R

      • Receptor: GRP-R

        Induced phenotype:

        • gatrointestinal motility
          • GRP modulates the gastrointestinal motility [3]
      • Receptor: galanin receptor 1

        Induced phenotype:

        • inhibition of circular muscle contraction
          • Galanin has an inhibitory role on circular muscle contraction in ileum.
      • Receptor: PRLR

      Reference