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Details for anatomical structure: peripheral blood mononuclear cell (PBMC)

EndoNet ID: ENC00426

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Synonyms

peripheral blood mononuclear cell (PBMC), ,

Links to other resources

Larger structures

    Substructures

      Secreted hormones

      • Hormone: IL-1 beta

      • Hormone: TNF-alpha

        Influenced by:

        • TLR2
          in peripheral blood mononuclear cell (PBMC)
          • The products of gram-positive bacteria may be promoting increases in circulating TNF-alpha and soluble TNF-alpha receptor via stimulation of TLR-2. [1]
      • Hormone: IFN-gamma

      • Hormone: IL-5

        • IL-5 production by PBMC upon stimulation with house dust mite (HDM) in patients with atopic dermatitis (AD) was significantly higher than that in non-atopic controls. [2]
      • Hormone: resistin

        • Human resistin was predominant expressed in mononuclear cells and low/absent in human adipocytes. [3]

      Receptors

      • Receptor: glucocorticoid receptor

      • Receptor: beta-2 adrenoreceptor

      • Receptor: TLR2

        Influences:

        • TNF-alpha
          • The products of gram-positive bacteria may be promoting increases in circulating TNF-alpha and soluble TNF-alpha receptor via stimulation of TLR-2. [1]
      • Receptor: TLR4

      Reference