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Details for anatomical structure: acinar cell of pancreas

EndoNet ID: ENC00439

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Synonyms

acinar cell of pancreas, , Exocrinocytus pancreaticus

General information

secreting digestiv enzymes and bicarbonate

Links to other resources

Cytomer cy0011188

Larger structures

    Substructures

      Secreted hormones

      • Hormone: FGF-1 isoform 1

      • Hormone: FGF-2

      Receptors

      • Receptor: VPAC1

        • Both VPAC1 and VPAC2 subtypes exist on pancreatic acini of rat and guinea pig. [1]

        Induced phenotype:

        • positive regulation of secretion
          • Both VIP receptor subtypes exist on pancreatic acini of rat and guinea pig, their activation stimulates enzyme secretion by a cAMP-mediated mechanism, and the effects of VIP are mediated 90% by activation of VPAC1 and 10% by VPAC2. [1]
      • Receptor: VPAC2

        • Both VPAC1 and VPAC2 subtypes exist on pancreatic acini of rat and guinea pig. [1]

        Induced phenotype:

        • positive regulation of secretion
          • Both VIP receptor subtypes exist on pancreatic acini of rat and guinea pig, their activation stimulates enzyme secretion by a cAMP-mediated mechanism, and the effects of VIP are mediated 90% by activation of VPAC1 and 10% by VPAC2. [1]
      Reference