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Details for anatomical structure: epithelial cell with microvilli

EndoNet ID: ENC00450

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Synonyms

epithelial cell with microvilli, , Epitheliocytus microvillosus

General information

lines highly absorptive surfaces

Links to other resources

Cytomer cy0011508

Larger structures

    Substructures

      Secreted hormones

      • Hormone: interleukin 6

      • Hormone: HB-EGF

        Influenced by:

        • PAF-R
          in epithelial_cell_with_microvilli
      • Hormone: mucin-2

        Influenced by:

        • EGFR isoform a
          in epithelial_cell_with_microvilli
          • PAFR transduces the signal to EGFR via ADAM10-dependent proteolysis of transmembrane HB-EGF. [1]
      • Hormone: IL-8

        Influenced by:

        • IL-1RI
          in epithelial_cell_with_microvilli
          • IL-1beta and NE (neutrophil elastase) stimulate IL-8 protein production and activate p38 MAPK in bronchial epithelial cells. [2]
        • TNFR1
          in epithelial_cell_with_microvilli
      • Hormone: ICAM-1

        • ICAM-1 expression was up-regulated in a cystic fibrosis cell line. [3]
      • Hormone: BD-1

      • Hormone: ENA-78

      • Hormone: GROalpha

      • Hormone: GRObeta

      • Hormone: GROgamma

      • Hormone: oncostatin M

      • Hormone: GM-CSF

      • Hormone: VEGF-165

      • Hormone: eotaxin-2

      • Hormone: eotaxin-3

      • Hormone: eotaxin

        • Unstimulated cells did not release detectable amounts of CCL11. [4]
        • Cytokine-stimulated alveolar type II epithelial cells express all three eotaxins and possess CCR3 receptors. [4]

        Influenced by:

        • TNFR1
          in epithelial_cell_with_microvilli
      • Hormone: SLPI

        • Expression of the SLPI gene has been extensively examined in superficial epithelial cells from human airways, but SLPI secretion from the superficial epithelium has not yet been clarified [5]
        • SLPI is predominantly in the serous cells of tracheal and bronchial submucosal glands [5]
      • Hormone: fibrinogen

        Influenced by:

        • IL-6R
          in epithelial_cell_with_microvilli
          • We determined the role of IL-6-receptor-gp130-Stat3 signaling in IL-6 activation of the γFBG promoter in liver and lung epithelial cells. [6]

      Receptors

      • Receptor: EGFR isoform a

        Influences:

        • mucin-2
          • PAFR transduces the signal to EGFR via ADAM10-dependent proteolysis of transmembrane HB-EGF. [1]
      • Receptor: PAF-R

        Influences:

        • HB-EGF
      • Receptor: TLR4

      • Receptor: TLR1

      • Receptor: TLR2

      • Receptor: TLR3

      • Receptor: TLR5

      • Receptor: TLR9

      • Receptor: CD14

      • Receptor: IL-1RI

        Influences:

        • IL-8
          • IL-1beta and NE (neutrophil elastase) stimulate IL-8 protein production and activate p38 MAPK in bronchial epithelial cells. [2]
      • Receptor: TLR6

      • Receptor: CCR3

      • Receptor: TNFR1

        Influences:

        • eotaxin
        • IL-8
      • Receptor: IL-4Ralpha

      • Receptor: IL-6R

        Influences:

        • fibrinogen
          • We determined the role of IL-6-receptor-gp130-Stat3 signaling in IL-6 activation of the γFBG promoter in liver and lung epithelial cells. [6]
      Reference