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Details for anatomical structure: alveolar macrophage

EndoNet ID: ENC00460

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Synonyms

alveolar macrophage, dust cell, Macrophagocytus stabilis

General information

Phagocytic cell in the alveoli, pick up dust or blood pigments

Links to other resources

Cytomer cy0011375

Larger structures

    Substructures

      Secreted hormones

      • Hormone: elafin

      Receptors

      • Receptor: calcitonin-receptor-like receptor

      • Receptor: TLR2

        Influences:

        • TNF-alpha
          • SP-A significantly reduced PGN-elicited tumor necrosis factor alpha (TNF-alpha) secretion by rat alveolar macrophages. The inhibitory effect on TNF-alpha secretion was dependent upon SP-A concentrations in physiological range. [1]
          • Direct interaction of SP-A with TLR2 alters PGN-induced cell signaling. [1]
      Reference