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Details for anatomical structure: alveolar macrophage

EndoNet ID: ENC00460

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Synonyms

alveolar macrophage, dust cell, Macrophagocytus stabilis

General information

Phagocytic cell in the alveoli, pick up dust or blood pigments

Links to other resources

Cytomer cy0011375

Larger structures

  • skeleton_muscle
  • muscle
  • parts_of_human_body
  • digestive_system
  • lymph_node
  • immune_system
  • caecum
  • appendix
  • lung
  • large_intestine

Substructures

    Secreted hormones

    • Hormone: elafin

    Receptors

    • Receptor: calcitonin-receptor-like receptor

    • Receptor: TLR2

      Influences:

      • TNF-alpha
        • SP-A significantly reduced PGN-elicited tumor necrosis factor alpha (TNF-alpha) secretion by rat alveolar macrophages. The inhibitory effect on TNF-alpha secretion was dependent upon SP-A concentrations in physiological range. [1]
        • Direct interaction of SP-A with TLR2 alters PGN-induced cell signaling. [1]
    Reference