Status
Please wait ...

Details for anatomical structure: Müllers radial cell of retina

EndoNet ID: ENC00468

To link to the content of EndoNet use the EndoNet ID that is given on the detail pages in the format ENX0000, where X is a place holder for the type of the component (e. g. R for receptor or C for anatomical structure).
As URL for the linking append this ID to the detail page for this type of component.
For an hormone that would be:

http://endonet.bioinf.med.uni-goettingen.de/hormone/ENH00000

It is also possible to use the search of EndoNet to link to the right detail page. The URL should look like

http://endonet.bioinf.med.uni-goettingen.de/search/ENC00000
If the search pattern is unambigious the user is directed to the corresponding detail page.

Synonyms

Müllers radial cell of retina, , Gliocytus radialis

General information

retinal glia cell

Links to other resources

Cytomer cy0011430

Larger structures

    Substructures

      Secreted hormones

      • Hormone: VEGF-183

      • Hormone: VEGF-165

      Receptors

      • Receptor: Vascular endothelial growth factor receptor 2

        • Isolated retinal Muller cells express both VEGF1 and VEGFR2 receptors. [1]

        Induced phenotype:

        • regulation of neural retina development
          • Extravascular VEGFR-1 and -2 are necessary for normal neural retinal development independent of vascular development. [1]
          • Peripheral retina is normally avascular at birth and becomes vascularized over the first 2 weeks after birth. [2]
          • Inhibition of VEGFR-1 and -2 in vivo inhibits development of the nonvascularized immature retina, resulting in cell loss in the inner retina, including the inner nuclear layer containing Muller cells and the ganglion cell layer containing astrocytes. [1]
      • Receptor: Vascular endothelial growth factor receptor 1

        • Isolated retinal Muller cells express both VEGF1 and VEGFR2 receptors. [1]

        Induced phenotype:

        • regulation of neural retina development
          • Extravascular VEGFR-1 and -2 are necessary for normal neural retinal development independent of vascular development. [1]
          • Peripheral retina is normally avascular at birth and becomes vascularized over the first 2 weeks after birth. [2]
          • Inhibition of VEGFR-1 and -2 in vivo inhibits development of the nonvascularized immature retina, resulting in cell loss in the inner retina, including the inner nuclear layer containing Muller cells and the ganglion cell layer containing astrocytes. [1]
      Reference