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Details for anatomical structure: zymogenic cell of gastric gland

EndoNet ID: ENC00469

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Synonyms

zymogenic cell of gastric gland, chief cell, pepsinogen cell, peptic cell, Exogenocytus principalis

General information

Predominate in the fundus, secreting pepsinogen. Epithelial cells that line the basal half of the gastric glands. Chief cells synthesise and secrete pepsinogen, a precursor of the enzyme pepsin.

Links to other resources

Cytomer cy0011186

Larger structures

    Substructures

      Secreted hormones

      • Hormone: REG1A

      Receptors

      • Receptor: CCK-1

      • Receptor: sst1

        Induced phenotype:

        • inhibition of pepsinogen release
          • Inhibition of pepsinogen release is caused by SST or by sympathetic stimulation. [1]
      Reference