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Synonyms
fat cell of brown fat, ,
General information
multilocular, large cell; enourmous number of mitochondria (responsible for brown colour); main function is heatproduction (without the typical shiver-side effect), by uncoupling the oxidative phosphorylation with the help of Thermogenin;
Prolactin combined with insulin significantly increases leptin expression and release from differentiated brown adipocytes, indicating that prolactin potentiates the stimulatory effect of insulin as revealed by the recruitment of insulin receptor substrates and the activation of phosphatidylinositol 3-kinase. [1]
Prolactin is not directly involved in transcription rate, but more likely in the secretion or release process of leptin in vivo. [1]
Prolactin combined with insulin significantly increases leptin expression and release from differentiated brown adipocytes, indicating that prolactin potentiates the stimulatory effect of insulin as revealed by the recruitment of insulin receptor substrates and the activation of phosphatidylinositol 3-kinase. [1]
Prolactin is not directly involved in transcription rate, but more likely in the secretion or release process of leptin in vivo. [1]