Details for anatomical structure: dorsal root ganglion
- Top
- General information
- Related structures
- Hormones
- Receptors
-
Click to access the toolbox
- Top
- General information
- Related structures
- Hormones
- Receptors
-
Click to access the toolbox
To link to the content of EndoNet use the EndoNet ID that is given on the detail
pages in the format ENX0000, where X is a place holder for the type of
the component (e. g. R for receptor or C for anatomical structure).
As URL
for the linking append this ID to the detail page for this type of component.
For an hormone that would be:
http://endonet.bioinf.med.uni-goettingen.de/hormone/ENH00000
It is also possible to use the search of EndoNet to link to the right detail page. The URL should look like
http://endonet.bioinf.med.uni-goettingen.de/search/ENC00000If the search pattern is unambigious the user is directed to the corresponding detail page.
Synonyms
dorsal root ganglion, dorsal root ganglia, spinal ganglion, Ganglion sensorium nervi spinalisGeneral information
Ganglia of dorsal roots of spinal nervesLinks to other resources
Cytomer | cy0023703 |
Related structures
Larger structures
Substructures
Secreted hormones
Receptors
-
Receptor: Transient receptor potential cation channel subfamily V member 1
Induced phenotype:
- sensory perception of pain
- VR1 is essential for the development of sensitization to thermal stimuli during inflammation but not for the normal sensation of noxious heat. [1]
-
Receptor: TrpV4-A
Induced phenotype:
- multicellular organismal water homeostasis
- Blockers of TRPV4 Attenuate the Hypotonic Stimulus-Induced [Ca2+]i Increase in Nociceptors, this suppoprt the involvement of TRPV4 in nociceptor osmosensitivity.
- TRPV4 is a transducer of osmotic stimulation in primary afferent nociceptive nerve fibers, and a transducer involved in inflammatory pain.
- multicellular organismal water homeostasis
-
Receptor: trkC
Induced phenotype:
- proprioception
- TrkC deficient mice display abnormal movements that are athetotic in nature and result in highly abnormal limb postures. This suggests a defect in proprioception, the sensory function that localizes the limbs in space. [2]
- Neurotrophin signaling through trk receptors is important in the development and maintenance of the mammalian nervous system. [3]
- Mice lacking trkC have a loss of DRG neurons, this defect might be amongst other responsible for the abnormal movements. [3]
- proprioception
-
Receptor: trkB
Induced phenotype:
-
Receptor: trkA
Induced phenotype:
- thermoception
- Neuroanatomical examinatio of the PNS of mice lacking trkA revealed extensive neuronal cell loss in trigeminal, dorsal root, and sympathetic ganglia. [5]
- Mice lacking the trkA exhibit deficiencies in thermoception. [3]
- Neurotrophin signaling through trk receptors is important in the development and maintenance of the mammalian nervous system. [3]
- thermoception