To link to the content of EndoNet use the EndoNet ID that is given on the detail
pages in the format ENX0000, where X is a place holder for the type of
the component (e. g. R for receptor or C for anatomical structure).
As URL
for the linking append this ID to the detail page for this type of component.
For an hormone that would be:
Levels of the CRF-R2 mRNA in the VMH were significantly lower in diabetic rats. Expression of CRF-R2 is mostly related to the insulin, but not to the corticosterone, status. Alterations in the brain CRF system due to insulin deficiency may contribute to the hyperdipsia in diabetes. [1]
Basal HPA axis may also be affected by magnocellular CRF that directly stimulates the AVP secretion through a paracrine mechanism at the level of neurohemal zone of the neurohypophysis. [1]
Levels of the CRF-R2 mRNA in the VMH were significantly lower in diabetic rats. Expression of CRF-R2 is mostly related to the insulin, but not to the corticosterone, status. Alterations in the brain CRF system due to insulin deficiency may contribute to the hyperphagia in diabetes. [1]
Levels of the CRF-R2 mRNA in the VMH were significantly lower in diabetic rats. Expression of CRF-R2 is mostly related to the insulin, but not to the corticosterone, status. Alterations in the brain CRF system due to insulin deficiency may contribute to the hyperdipsia in diabetes. [1]
The VMH is a brain region seemingly involved in the modulation of insulin secretion as ablation of the VMH led to increase in the parasympathetic tone to the pancreas and insulin oversecretion. [2]
There is evidence that the CRF-R2 in the VMH mediates the anorectic effects of CRF. [3]
A part of insulin central effects may be mediated through its regulation of CRF-R2 VMH expression. [1]