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Details for messenger / hormone: 5alpha-androstanediol

EndoNet ID: ENH00002

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Synonyms

  • 3alpha-diol
  • 5alpha-androstane-3alpha, 17beta-diol
  • adiol
  • androstane-3,17-diol
  • 5alpha-androstanediol
  • 3alpha5alphaAdiol

General information

  • Urinary androstanediol measurement, often in association with other androgens, is commonly used to support the clinical diagnosis of idiopathic hirsutism. In addition, androgen excess has been shown to be the endocrine abnormality which characterizes patients with breast cancer. [1]
  • 3alpha-diol has positive effect in locomotion and analgesia of male hamsters. [2]

Classification

Hormone function

  • CNS function
    • stress response
      • motor activity

      Chemical classification

      • hormone
        • not genome-encoded

      Composition

      KEGG C07632

      Links to other resources

      KEGG C07632
      LIPID MAPS LMST02020052

        Targets

        CellSHBG-R
        prostate Present
        Influences
        • ↑ free PSA
        Reference