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Details for messenger / hormone: GHRH

EndoNet ID: ENH00078

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Synonyms

  • GHRH
  • SRF
  • SRH
  • somatotropin-releasing factor
  • somatocrinin
  • growth hormone-releasing factor
  • GHRF
  • GH-RF
  • growth hormone-releasing hormone
  • somatoliberin
  • Somatorelin

General information

  • Induces the release of somatotropin (growth hormone). [1]
  • Peptide hormone. [2]

Classification

Hormone function

  • homeostasis
    • further hormone secretion

    Chemical classification

    Composition

    Sequence 
    YADAIFTNS YRKVLGQLS ARKLLQDIM 
SRQQGESNQ ERGARARL

    Links to other resources

    UniProt P01286
    Ensembl ENST00000373614
    KEGG hsa:2691

    • Anatomical structure: arcuate_nucleus_of_hypothalamus

      Influenced by:

      • PRLR
        in arcuate_nucleus_of_hypothalamus

    Targets

    CellGHRH-R
    acidophil somatotroph cell of anterior pituitary Present
    Phenotypes
    • Growth hormone deficiency
    • dwarfism
    Influences
    • ↑ GH
    adenohypophysis Present
    Phenotypes
    • dwarfism
    pituitary gland of diencephalon Present
    Phenotypes
    • dwarfism
    Reference