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Details for messenger / hormone: ADM2

EndoNet ID: ENH00138

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Synonyms

  • Intermedin-long
  • IMD
  • ADM2
  • adrenomedullin 2
  • intermedin

General information

  • Intermedin is expressed primarily in the pituitary and gastrointestinal tract. [1]
  • Acts through the calcitonin receptor-like receptor/receptor activity-modifying protein receptor complexes. [1]
  • Intermedin represents a nonselective agonist for the RAMP coreceptors. [1]
  • Intermedin (IMD) is a member of the calcitonin/calcitonin gene-related peptide (CT/CGRP) family identified from human and other vertebrate tissues. [2]

Classification

Hormone function

  • homeostasis
    • cardiovascular control
    • metabolism
      • nutrient supply

      Chemical classification

      • hormone
        • genome-encoded

      Composition

      Sequence
      TQAQLLRVG CVLGTCQVQ NLSHRLWQL 
      MGPAGRQDS APVDPSSPH SY

      Links to other resources

      UniProt Q7Z4H4
      Ensembl ENST00000395738
      KEGG hsa:79924

        Targets

        Reference