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Details for messenger / hormone: CGRP2

EndoNet ID: ENH00145

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Synonyms

  • CGRP-II
  • calcitonin gene-related peptide II
  • calcitonin gene-related peptide 2
  • CGRP2
  • beta-type CGRP
  • beta-CGRP
  • calcitonin-related peptide ll
  • CALC2
  • CALCB
  • calcitonin-related polypeptide beta

General information

  • This gene encodes a second human CGRP, differing from the known human CGRP in 3 of the 37 amino acids. [1]

Classification

Hormone function

  • homeostasis
    • cardiovascular control

    Chemical classification

    • hormone
      • genome-encoded
        • calcitonin family

      Composition

      Sequence
      ACNTATCVT HRLAGLLSR SGGMVKSNF 
      VPTNVGSKA F

      Links to other resources

      UniProt P10092
      Ensembl ENST00000396377
      KEGG hsa:797
      • Anatomical structure: brain

      • Anatomical structure: thyroid_gland

      Targets

      Cellcalcitonin receptorcalcitonin-receptor-like receptor
      alveolar macrophage Present
      area postrema of pons Present
      blood vessel Present
      cardiac myocyte Present
      cell of adrenal gland zona reticularis Present
      endocardium Present
      juxtaglomerular apparatus Present
      Leydig cell of testis Present
      lung Present
      mucosa of gastric wall Present
      nucleus accumbens Present
      osteoblast Present
      osteoclast Present
      Phenotypes
      • osteoporosis
      pancreatic islets Present
      Reference