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Details for messenger / hormone: GnRH-II (Isoform 1)

EndoNet ID: ENH00146

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Synonyms

  • GnRH-associated peptide II
  • luliberin II
  • gonadotropin-releasing hormone II
  • luteinizing hormone-releasing hormone II
  • gonadoliberin II
  • progonadoliberin II
  • GnRH-II (Isoform 1)
  • GNRH2
  • gonadotropin-releasing hormone 2
  • luliberin 2
  • gonadocrinin
  • ovarian GnRH
  • Progonadoliberin-2

General information

  • This form is extra-hypothalamic and may have no direct involvement in gonadotropin regulation. [1]
  • It may have a neurotransmitter or neromodulatory function and is generally localized in areas outside the hypothalamus, particularly in midbrain regions. [1]

Classification

Hormone function

  • development and growth
    • environment adaptation

    Chemical classification

    • hormone
      • genome-encoded
        • GnRH family

      Composition

      GnRH-associated peptide 2

      Sequence
      ALSSAQDPQ NALRPPGRA LDTAAGSPV 
      QTAHGLPSD ALAPLDDSM PWEGRTTAQ 
      WSLHRKRHL ARTLLTAAR EPRPAPPSS 
      NKV

      Gonadoliberin-2

      • Progonadoliberin-2 is cleaved into Gonadoliberin-2 and GnRH-associated peptide 2.
      Sequence
      QHWSHGWYP G

      Links to other resources

      UniProt O43555
      Ensembl ENST00000245983
      KEGG hsa:2797
      • Anatomical structure: kidney

      • Anatomical structure: bone_marrow

      • Anatomical structure: prostate

      Targets

      Reference