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Details for messenger / hormone: hCG

EndoNet ID: ENH00149

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Synonyms

  • chorionic gonadotrophin chain beta
  • choriogonadotropin subunit beta
  • hCG
  • chorionic gonadotropin

General information

  • Heterodimer of the common alpha and any beta subunit (beta, beta1, beta2, beta5, beta7, beta8).

Classification

Hormone function

  • homeostasis
    • further hormone secretion
    • reproduction and sexual differentiation
      • reproduction

      Chemical classification

      • hormone
        • genome-encoded
          • glycoprotein hormones family
            • gonadotropic hormones

        Composition

        alpha (1 times)

        Sequence
        APDVQDCPE CTLQENPFF SQPGAPILQ 
        CMGCCFSRA YPTPLRSKK TMLVQKNVT 
        SESTCCVAK SYNRVTVMG GFKVENHTA 
        CHCSTCYYH KS
        UniProt P01215

        beta (1 times)

        Sequence
        SKEPLRPRC RPINATLAV EKEGCPVCI 
        TVNTTICAG YCPTMTRVL QGVLPALPQ 
        VVCNYRDVR FESIRLPGC PRGVNPVVS 
        YAVALSCQC ALCRRSTTD CGGPKDHPL 
        TCDDPRFQD SSSSKAPPP SLPSPSRLP 
        GPSDTPILP Q
        UniProt P01233

        Links to other resources

        UniProt P01233
        Ensembl ENST00000448456
        KEGG hsa:94115
        • Anatomical structure: placenta

        Targets

        CellLHCGR-1
        cell of adrenal gland zona glomerulosa Present
        Influences
        • progesterone
        granulosa cell Present
        Phenotypes
        • regulation of ovulation
        Influences
        • progesterone
        • estrogen
        Leydig cell of testis Present
        Influences
        • testosterone
        theca cell Present
        Influences
        • androstenedione
        • testosterone
        Reference