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Details for messenger / hormone: orexin-B

EndoNet ID: ENH00159

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  • orexin-B
  • Hypocretin-1
  • Hypocretin
  • Orexin
  • hypocretin-2
  • Hcrt2

General information

  • Orexins, after the Greek word "orexis," which means appetite, have a physiological role in the stimulation of food intake. [1]


Hormone function

  • CNS function
    • circadian rhythm / sleep
    • metabolism
      • nutrient supply

      Chemical classification

      • hormone
        • genome-encoded
          • peptide neurotransmitters

      Links to other resources

      UniProt O43612
      Ensembl ENST00000293330
      KEGG hsa:3060
      • Anatomical structure: lateral_hypothalamic_area

        Influenced by:

        • orexin receptor 1
          in lateral_hypothalamic_area
        • leptin receptor isoform b
          in hypothalamus
          • Leptin inhibts the secretion of orexin