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Details for messenger / hormone: RELMbeta

EndoNet ID: ENH00186

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Synonyms

  • FIZZ2
  • colon and small intestine-specific cysteine-rich protein
  • RELMbeta
  • resistin-like beta
  • RSNB
  • HXCP2
  • RELM-alpha
  • RELMa
  • RELMB
  • RELMb
  • XCP2
  • resistin-like molecule beta
  • found in inflammatory zone 2
  • cysteine-rich secreted protein FIZZ2
  • cysteine-rich secreted protein A12-alpha-like 1
  • colon carcinoma-related gene protein
  • RETNLB

General information

  • RELMbeta/FIZZ2 is a goblet cell-specific immune-effector molecule in the gastrointestinal tract. [1]
  • Human RELMbeta is a mitogenic factor in lung cells and induced in hypoxia. [2]

Classification

Hormone function

  • homeostasis
    • further hormone secretion
    • development and growth
      • growth stimulation

      Chemical classification

      • hormone
        • genome-encoded
          • cytokines

      Composition

      Resistin-like beta

      Sequence
      QCSLDSVMD KKIKDVLNS LEYSPSPIS 
      KKLSCASVK SQGRPSSCP AGMAVTGCA 
      CGYGCGSWD VQLETTCHC QCSVVDWTT 
      ARCCHLT

      Links to other resources

      UniProt Q9BQ08
      Ensembl ENST00000295755
      KEGG hsa:84666
      • Anatomical structure: colon

      • Anatomical structure: large_intestine

      • Anatomical structure: small_intestine

      Targets

      Cell
      No records found.
      Reference