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Details for messenger / hormone: SAA

EndoNet ID: ENH00205

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Synonyms

  • amyloid fibril protein AA
  • SAA
  • serum amyloid A protein
  • serum amyloid A
  • Apo-SAA

General information

  • Expression of SAA predominantly in the liver. [1]
  • Serum amyloid A (SAA), the precursor to amyloid A protein found in secondary amyloid plaques, consists of a family of apolipoproteins which bind to, and substitute for, apo A-I in HDL. [1]
  • Pro-inflammatory and anti-inflammatory roles. [1]
  • Function: proposed mediators of inflammation and chronic hyperglycemia, thus they might link inflammation to the development of obesity. [2]

Classification

Hormone function

  • immune response
    • activation
    • metabolism

    Chemical classification

    Composition

    Serum amyloid A protein.

    Sequence
    RSFFSFLGE AFDGARDMW RAYSDMREA 
    NYIGSDKYF HARGNYDAA KRGPGGVWA 
    AEAISDARE NIQRFFGHG AEDSLADQA 
    ANEWGRSGK DPNHFRPAG LPEKY
    UniProt P02735

    Links to other resources

    UniProt P02735
    Ensembl ENST00000405158
    KEGG hsa:6289
    • Anatomical structure: fat_cell

    Targets

    Cell
    No records found.
    Reference