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Details for messenger / hormone: GROgamma

EndoNet ID: ENH00286

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Synonyms

  • GROG
  • GRO-gamma(1-73)
  • growth-regulated protein gamma
  • macrophage inflammatory protein 2-beta
  • C-X-C motif chemokine 3
  • GROgamma
  • CXCL3
  • GRO gamma
  • GRO3 oncogene
  • GRO3
  • growth related oncogene gamma
  • MIP-2beta
  • SCYB3
  • GRO-gamma
  • small inducible cytokine B3
  • GRO protein gamma
  • macrophage inflammatory protein 2 beta
  • MIP2B

General information

  • Cytokine with inflammatory and growth-regulatory properties [1]
  • Expression of the cytokine gene gro, also known as melanoma growth stimulatory activity, is induced by inflammatory stimuli, including IL-1. [2]
  • Chemotactic activity for neutrophils.

Classification

Hormone function

  • immune response
    • activation

    Chemical classification

    • hormone
      • genome-encoded
        • cytokines
          • chemokines
            • CXC chemokines

      Links to other resources

      UniProt P19876
      Ensembl ENST00000296026
      KEGG hsa:2921
      • Anatomical structure: hepatocyte

      • Anatomical structure: bronchial_epithelial_cell

      • Anatomical structure: epithelial_cell_with_microvilli

      Targets

      CellCXCR1IL-8R B
      acidophil mammotroph cell of anterior pituitary Present
      Influences
      • PRL
      acidophil somatotroph cell of anterior pituitary Present
      Influences
      • GH
      basophil corticotroph cell of anterior pituitary Present
      Influences
      • ACTH
      basophil gonadotroph cell of anterior pituitary FSH Present
      Influences
      • FSH
      • LH
      basophil thyrotroph cell of anterior pituitary Present
      killer cell Present
      Present
      monocyte Present
      Present
      neutrophil granulocyte Present
      Present
      Reference