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Details for messenger / hormone: FGF-5

EndoNet ID: ENH00295

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Synonyms

  • FGF5
  • fibroblast growth factor 5
  • FGF-5
  • fibroblast growth factor-5
  • HBGF-5
  • heparin-binding growth factor 5
  • Smag-82

General information

  • Involved in hair growth and development.
  • FGF-5 can transform NIH 3T3 cells. [1]

Classification

Hormone function

  • development and growth
    • growth stimulation

    Chemical classification

    • hormone
      • genome-encoded
        • cytokines
          • heparin-binding growth factors

      Composition

      Sequence
      AWAHGEKRL APKGQPGPA ATDRNPRGS 
      SSRQSSSSA MSSSSASSS PAASLGSQG 
      SGLEQSSFQ WSPSGRRTG SLYCRVGIG 
      FHLQIYPDG KVNGSHEAN MLSVLEIFA 
      VSQGIVGIR GVFSNKFLA MSKKGKLHA 
      SAKFTDDCK FRERFQENS YNTYASAIH 
      RTEKTGREW YVALNKRGK AKRGCSPRV 
      KPQHISTHF LPRFKQSEQ PELSFTVTV 
      PEKKNPPSP IKSKIPLSA PRKNTNSVK 
      YRLKFRFG

      Links to other resources

      UniProt P12034
      Ensembl ENST00000312465
      KEGG hsa:2250

        Targets

        CellFGFR-1FGFR-2
        adrenal cortex Present
        Present
        brain Present
        Phenotypes
        • Kallmann syndrome 2
        • olfactory bulb morphogenesis
        cardiac muscle Present
        Phenotypes
        • regulation of cell proliferation
        Present
        Phenotypes
        • regulation of cell proliferation
        cerebral cortex Present
        Phenotypes
        • regulation of neuron differentiation
        chondrocyte Present
        endocardium Present
        Reference