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Details for messenger / hormone: MDC

EndoNet ID: ENH00335

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Synonyms

  • MDC
  • stimulated T-cell chemotactic protein 1
  • MDC(1-69)
  • small-inducible cytokine A22
  • C-C motif chemokine 22
  • A-152E5.1
  • small inducible cytokine A22
  • CC chemokine STCP-1
  • CCL22
  • Dctactin-beta
  • macrophage-derived chemokine
  • SCYA22
  • STCP-1
  • stimulated T cell chemotactic protein 1
  • chemokine (C-C motif) ligand 22

General information

  • Chemotactic for monocytes, dendritic cells and natural killer cells. [1]
  • Macrophage-derived chemokine is a functional ligand for the CC chemokine receptor 4. [2]

Classification

Hormone function

  • immune response
    • activation

    Chemical classification

    • hormone
      • genome-encoded
        • cytokines
          • chemokines
            • CC chemokines

      Composition

      Sequence 
      GPYGANMED SVCCRDYVR YRLPLRVVK 
HFYWTSDSC PRPGVVLLT FRDKEICAD 
PRVPWVKMI LNKLSQ

      Links to other resources

      UniProt O00626
      Ensembl ENST00000219235
      KEGG hsa:6367

      • Anatomical structure: macrophage

      • Anatomical structure: pancreas

      • Anatomical structure: spleen

      • Anatomical structure: dendritic_cell_in_lymphoid_tissues

      • Anatomical structure: thymus

      • Anatomical structure: monocyte

      • Anatomical structure: lung

      Targets

      CellCCR4
      basophil granulocyte Present
      helper T cell Th1 Present
      platelet Present
      T-lymphocyte Present
      thymus Present
      Reference