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Details for messenger / hormone: Emap2

EndoNet ID: ENH00336

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Synonyms

  • endothelial monocyte-activating polypeptide II
  • aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
  • Emap2
  • EMAP-II
  • EMAPII
  • endothelial-monocyte activating polypeptide II
  • multisynthetase complex auxiliary component p43
  • SCYE1
  • small inducible cytokine subfamily E member 1

General information

  • Endothelial-monocyte-activating polypeptide II (EMAPII) is an inflammatory cytokine released under apoptotic conditions. [1]
  • Its proEMAPII precursor proved to be identical to the auxiliary p43 component of the aminoacyl-tRNA synthetase complex. [1]

Classification

Hormone function

  • immune response
    • activation
    • metabolism
      • nutrient supply

      Chemical classification

      • hormone
        • genome-encoded
          • cytokines
            • chemokines

      Composition

      Sequence
      SKPIDVSRL DLRIGCIIT ARKHPDADS 
      LYVEEVDVG EIAPRTVVS GLVNHVPLE 
      QMQNRMVIL LCNLKPAKM RGVLSQAMV 
      MCASSPEKI EILAPPNGS VPGDRITFD 
      AFPGEPDKE LNPKKKIWE QIQPDLHTN 
      DECVATYKG VPFEVKGKG VCRAQTMSN 
      SGIK

      Links to other resources

      UniProt Q12904
      Ensembl ENST00000442366
      KEGG hsa:9255
      • Anatomical structure: cell_of_endometrium_of_uterus

        • EMAP II expression is negatively regulated by PGE2. [2]

      Targets

      CellCXCR3
      killer cell Present
      monocyte Present
      Reference