Status
Please wait ...

Details for messenger / hormone: activin B

EndoNet ID: ENH00359

To link to the content of EndoNet use the EndoNet ID that is given on the detail pages in the format ENX0000, where X is a place holder for the type of the component (e. g. R for receptor or C for anatomical structure).
As URL for the linking append this ID to the detail page for this type of component.
For an hormone that would be: 

http://endonet.bioinf.med.uni-goettingen.de/hormone/ENH00000

It is also possible to use the search of EndoNet to link to the right detail page. The URL should look like 

http://endonet.bioinf.med.uni-goettingen.de/search/ENC00000
If the search pattern is unambigious the user is directed to the corresponding detail page.

Synonyms

  • activin beta-B
  • inhibin beta-2
  • activin B

General information

  • Inhibin beta B has a novel role in establishing sex-specific gonad vasculature. [1]
  • Regulates embryogenesis, osteogenesis, hematopoiesis, reproductive physiology and hormone secretion from the hypothalamic, pituitary and gonadal glands.

Classification

Hormone function

  • development and growth
    • embryogenesis

    Chemical classification

    • hormone
      • genome-encoded
        • cytokines
          • TGF-beta family

      Composition

      activin beta-B chain (2 times)

      • Activin B is a homodimer of beta-B.
      Sequence 
      GLECDGRTN LCCRQQFFI DFRLIGWND 
WIIAPTGYY GNYCEGSCP AYLAGVPGS 
ASSFHTAVV NQYRMRGLN PGTVNSCCI 
PTKLSTMSM LYFDDEYNI VKRDVPNMI 
VEECGCA
      UniProt P09529

      Links to other resources

        Targets

        CellALK7
        adipose tissue Present
        Phenotypes
        • regulation of adipose-tissue homeostasis
        Reference