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Details for messenger / hormone: activin AB

EndoNet ID: ENH00360

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Synonyms

  • activin beta A and beta B
  • activin AB

General information

  • Regulates embryogenesis, osteogenesis, hematopoiesis, reproductive physiology and hormone secretion from the hypothalamic, pituitary and gonadal glands.

Classification

Hormone function

  • development and growth
    • embryogenesis

    Chemical classification

    • hormone
      • genome-encoded
        • cytokines
          • TGF-beta family

      Composition

      inhibin beta B chain (1 times)

      Sequence
      GLECDGRTN LCCRQQFFI DFRLIGWND 
      WIIAPTGYY GNYCEGSCP AYLAGVPGS 
      ASSFHTAVV NQYRMRGLN PGTVNSCCI 
      PTKLSTMSM LYFDDEYNI VKRDVPNMI 
      VEECGCA
      UniProt P09529

      inhibin beta A chain (1 times)

      Sequence
      GLECDGKVN ICCKKQFFV SFKDIGWND 
      WIIAPSGYH ANYCEGECP SHIAGTSGS 
      SLSFHSTVI NHYRMRGHS PFANLKSCC 
      VPTKLRPMS MLYYDDGQN IIKKDIQNM 
      IVEECGCS
      UniProt P08476

      Links to other resources

        Targets

        CellALK7
        adipose tissue Present
        Phenotypes
        • regulation of adipose-tissue homeostasis
        Reference