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Details for messenger / hormone: BMP5

EndoNet ID: ENH00365

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Synonyms

  • BMP5
  • BMP-5
  • bone morphogenetic protein 5

General information

  • GREMLIN and DANTE are secreted antagonists for BMPs and SLITs. [1]
  • The deficiency of BMP-5 prevents age-related decelerations in chondrocytic proliferation and initiation of hypertrophic differentiation. [2]
  • Induces cartilage and bone formation. Expressed in the lung and liver. [3]

Classification

Hormone function

  • development and growth
    • growth stimulation

    Chemical classification

    • hormone
      • genome-encoded
        • cytokines
          • TGF-beta family

      Composition

      Sequence 
      NQNRNKSSS HQDSSRMSS VGDYNTSEQ 
KQACKKHEL YVSFRDLGW QDWIIAPEG 
YAAFYCDGE CSFPLNAHM NATNHAIVQ 
TLVHLMFPD HVPKPCCAP TKLNAISVL 
YFDDSSNVI LKKYRNMVV RSCGCH

      Links to other resources

      UniProt P22003
      Ensembl ENST00000370830
      KEGG hsa:653

      • Anatomical structure: lung

      • Anatomical structure: substantia_propria_of_cornea

      • Anatomical structure: corneal_endothelial_cell

      Targets

      Cell
      No records found.
      Reference