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Details for messenger / hormone: eotaxin-3

EndoNet ID: ENH00397

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Synonyms

  • CC chemokine IMAC
  • thymic stroma chemokine-1
  • small-inducible cytokine A26
  • C-C motif chemokine 26
  • eotaxin-3
  • macrophage inflammatory protein 4-alpha
  • CCL26
  • Eot-3

General information

  • Chemotactive for eosinophils and basophils. Binds to CCR3. [1]
  • Ubiquitously expressed at low levels in various tissues including heart and ovary. [1]

Classification

Hormone function

  • immune response
    • activation

    Chemical classification

    • hormone
      • genome-encoded
        • cytokines
          • chemokines
            • CC chemokines

      Composition

      small inducible cytokine A26

      Sequence
      TRGSDISKT CCFQYSHKP LPWTWVRSY 
      EFTSNSCSQ RAVIFTTKR GKKVCTHPR 
      KKWVQKYIS LLKTPKQL

      Links to other resources

      UniProt Q9Y258
      Ensembl ENST00000394905
      KEGG hsa:10344
      • Anatomical structure: heart

      • Anatomical structure: ovary

      • Anatomical structure: epithelial_cell_with_microvilli

      Targets

      Reference