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Details for messenger / hormone: CCL1

EndoNet ID: ENH00402

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Synonyms

  • small-inducible cytokine A1
  • C-C motif chemokine 1
  • CCL1
  • I-309
  • SCYA1
  • small inducible cytokine A1
  • T lymphocyte-secreted protein I-309

General information

  • Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8. [1]

Classification

Hormone function

  • immune response
    • activation

    Chemical classification

    • hormone
      • genome-encoded
        • cytokines
          • chemokines
            • CC chemokines

      Composition

      Sequence 
      KSMQVPFSR CCFSFAEQE IPLRAILCY 
RNTSSICSN EGLIFKLKR GKEACALDT 
VGWVQRHRK MLRHCPSKR K

      Links to other resources

      UniProt P22362
      Ensembl ENST00000225842
      KEGG hsa:6346

      • Anatomical structure: macrophage

        Influenced by:

        • AhR
          in macrophage
          • Polycyclic aromatic hydrocarbons (PAHs) induce expression of the chemokine CCL1 in an AhR- and calcium-dependent manner. [2]

      Targets

      CellCCR8
      No records found.
      Reference