Status
Please wait ...

Details for messenger / hormone: CCL28

EndoNet ID: ENH00408

To link to the content of EndoNet use the EndoNet ID that is given on the detail pages in the format ENX0000, where X is a place holder for the type of the component (e. g. R for receptor or C for anatomical structure).
As URL for the linking append this ID to the detail page for this type of component.
For an hormone that would be: 

http://endonet.bioinf.med.uni-goettingen.de/hormone/ENH00000

It is also possible to use the search of EndoNet to link to the right detail page. The URL should look like 

http://endonet.bioinf.med.uni-goettingen.de/search/ENC00000
If the search pattern is unambigious the user is directed to the corresponding detail page.

Synonyms

  • protein CCK1
  • small-inducible cytokine A28
  • C-C motif chemokine 28
  • CCL28
  • CC chemokine 28
  • MEC
  • mucosae-associated epithelial chemokine
  • SCYA28
  • small inducible cytokine A28
  • CCK1 protein

General information

  • Chemotactic activity for resting CD4, CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. [1]

Classification

Hormone function

  • immune response
    • activation

    Chemical classification

    • hormone
      • genome-encoded
        • cytokines
          • chemokines
            • CC chemokines

      Composition

      Sequence 
      SEAILPIAS SCCTEVSHH ISRRLLERV 
NMCRIQRAD GDCDLAAVI LHVKRRRIC 
VSPHNHTVK QWMKVQAAK KNGKGNVCH 
RKKHHGKRN SNRAHQGKH ETYGHKTPY

      Links to other resources

      UniProt Q9NRJ3
      Ensembl ENST00000361115
      KEGG hsa:56477

      • Anatomical structure: eosinophil_granulocyte

      • Anatomical structure: thyroid_gland

      • Anatomical structure: prostate

      • Anatomical structure: spleen

      • Anatomical structure: skin

      • Anatomical structure: ovary

      • Anatomical structure: colon

      Targets

      Reference