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Details for messenger / hormone: chondromodulin 2

EndoNet ID: ENH00456

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Synonyms

  • leukocyte cell-derived chemotaxin-2
  • chondromodulin II
  • leukocyte cell-derived chemotaxin 2
  • hLECT2
  • LECT2
  • leukocyte cell derived chemotaxin 2
  • chondromodulin 2
  • ChM-II

General information

  • Has a neutrophil chemotactic activity and is a positive regulator of chondrocyte proliferation. [1]
  • ChM-II does not inhibit vascularization but stimulates osteoclast differentiation. [2]
  • LECT2, which encodes a protein with chemotactic properties for human neutrophils, is a direct target gene of Wnt/beta-catenin signaling in the liver. [3]

Classification

Hormone function

  • development and growth
    • growth stimulation

    Chemical classification

    • hormone
      • genome-encoded
        • chemotaxins

      Composition

      Leukocyte cell-derived chemotaxin 2, chain

      Sequence 
      GPWANICAG KSSNEIRTC DRHGCGQYS 
AQRSQRPHQ GVDVLCSAG STVYAPFTG 
MIVGQEKPY QNKNAINNG VRISGRGFC 
VKMFYIKPI KYKGPIKKG EKLGTLLPL 
QKVYPGIQS HVHIENCDS SDPTAYL
      UniProt O14960

      Links to other resources

      UniProt O14960
      Ensembl ENST00000274507
      KEGG hsa:3950

      • Anatomical structure: blood

      • Anatomical structure: testis

        • Weakly expressed.

      • Anatomical structure: hepatocyte

      • Anatomical structure: spleen

      Targets

      Cell
      No records found.
      Reference