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Details for messenger / hormone: tenascin-C

EndoNet ID: ENH00462

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Synonyms

  • HXB
  • myotendinous antigen
  • cytotactin
  • glioma-associated-extracellular matrix antigen
  • tenascin
  • TN
  • hexabrachion
  • neuronectin
  • GMEM
  • JI
  • miotendinous antigen
  • GP 150-225
  • tenascin-C
  • TN-C
  • TNC

General information

  • Hexameric glycoprotein present in extracellular matrices, member of a family of related proteins comprising tenascin-C, tenascin-R, and tenascin-X. All of these proteins are modular proteins containing heptad repeat sequences, epidermal growth factor-like modules, fibronectin type III modules, and a fibrinogen-like domain. [1]
  • Tenascin is believed to be an important extracellular matrix protein involved in regulating numerous developmental processes, such as morphogenetic cell migration and organogenesis. [2]

Classification

Hormone function

  • development and growth
    • embryogenesis

    Chemical classification

    Composition

    Tenascin isoform 1

    Sequence
    GVLKKVIRH KRQSGVNAT LPEENQPVV 
    FNHVYNIKL PVGSQCSVD LESASGEKD 
    LAPPSEPSE SFQEHTVDG ENQIVFTHR 
    INIPRRACG CAAAPDVKE LLSRLEELE 
    NLVSSLREQ CTAGAGCCL QPATGRLDT 
    RPFCSGRGN FSTEGCGCV CEPGWKGPN 
    CSEPECPGN CHLRGRCID GQCICDDGF 
    TGEDCSQLA CPSDCNDQG KCVNGVCIC 
    FEGYAGADC SREICPVPC SEEHGTCVD 
    GLCVCHDGF AGDDCNKPL CLNNCYNRG 
    RCVENECVC DEGFTGEDC SELICPNDC 
    FDRGRCING TCYCEEGFT GEDCGKPTC 
    PHACHTQGR CEEGQCVCD EGFAGLDCS 
    EKRCPADCH NRGRCVDGR CECDDGFTG 
    ADCGELKCP NGCSGHGRC VNGQCVCDE 
    GYTGEDCSQ LRCPNDCHS RGRCVEGKC 
    VCEQGFKGY DCSDMSCPN DCHQHGRCV 
    NGMCVCDDG YTGEDCRDR QCPRDCSNR 
    GLCVDGQCV CEDGFTGPD CAELSCPND 
    CHGQGRCVN GQCVCHEGF MGKDCKEQR 
    CPSDCHGQG RCVDGQCIC HEGFTGLDC 
    GQHSCPSDC NNLGQCVSG RCICNEGYS 
    GEDCSEVSP PKDLVVTEV TEETVNLAW 
    DNEMRVTEY LVVYTPTHE GGLEMQFRV 
    PGDQTSTII QELEPGVEY FIRVFAILE 
    NKKSIPVSA RVATYLPAP EGLKFKSIK 
    ETSVEVEWD PLDIAFETW EIIFRNMNK 
    EDEGEITKS LRRPETSYR QTGLAPGQE 
    YEISLHIVK NNTRGPGLK RVTTTRLDA 
    PSQIEVKDV TDTTALITW FKPLAEIDG 
    IELTYGIKD VPGDRTTID LTEDENQYS 
    IGNLKPDTE YEVSLISRR GDMSSNPAK 
    ETFTTGLDA PRNLRRVSQ TDNSITLEW 
    RNGKAAIDS YRIKYAPIS GGDHAEVDV 
    PKSQQATTK TTLTGLRPG TEYGIGVSA 
    VKEDKESNP ATINAATEL DTPKDLQVS 
    ETAETSLTL LWKTPLAKF DRYRLNYSL 
    PTGQWVGVQ LPRNTTSYV LRGLEPGQE 
    YNVLLTAEK GRHKSKPAR VKASTEQAP 
    ELENLTVTE VGWDGLRLN WTAADQAYE 
    HFIIQVQEA NKVEAARNL TVPGSLRAV 
    DIPGLKAAT PYTVSIYGV IQGYRTPVL 
    SAEASTGET PNLGEVVVA EVGWDALKL 
    NWTAPEGAY EYFFIQVQE ADTVEAAQN 
    LTVPGGLRS TDLPGLKAA THYTITIRG 
    VTQDFSTTP LSVEVLTEE VPDMGNLTV 
    TEVSWDALR LNWTTPDGT YDQFTIQVQ 
    EADQVEEAH NLTVPGSLR SMEIPGLRA 
    GTPYTVTLH GEVRGHSTR PLAVEVVTE 
    DLPQLGDLA VSEVGWDGL RLNWTAADN 
    AYEHFVIQV QEVNKVEAA QNLTLPGSL 
    RAVDIPGLE AATPYRVSI YGVIRGYRT 
    PVLSAEAST AKEPEIGNL NVSDITPES 
    FNLSWMATD GIFETFTIE IIDSNRLLE 
    TVEYNISGA ERTAHISGL PPSTDFIVY 
    LSGLAPSIR TKTISATAT TEALPLLEN 
    LTISDINPY GFTVSWMAS ENAFDSFLV 
    TVVDSGKLL DPQEFTLSG TQRKLELRG 
    LITGIGYEV MVSGFTQGH QTKPLRAEI 
    VTEAEPEVD NLLVSDATP DGFRLSWTA 
    DEGVFDNFV LKIRDTKKQ SEPLEITLL 
    APERTRDLT GLREATEYE IELYGISKG 
    RRSQTVSAI ATTAMGSPK EVIFSDITE 
    NSATVSWRA PTAQVESFR ITYVPITGG 
    TPSMVTVDG TKTQTRLVK LIPGVEYLV 
    SIIAMKGFE ESEPVSGSF TTALDGPSG 
    LVTANITDS EALARWQPA IATVDSYVI 
    SYTGEKVPE ITRTVSGNT VEYALTDLE 
    PATEYTLRI FAEKGPQKS STITAKFTT 
    DLDSPRDLT ATEVQSETA LLTWRPPRA 
    SVTGYLLVY ESVDGTVKE VIVGPDTTS 
    YSLADLSPS THYTAKIQA LNGPLRSNM 
    IQTIFTTIG LLYPFPKDC SQAMLNGDT 
    TSGLYTIYL NGDKAQALE VFCDMTSDG 
    GGWIVFLRR KNGRENFYQ NWKAYAAGF 
    GDRREEFWL GLDNLNKIT AQGQYELRV 
    DLRDHGETA FAVYDKFSV GDAKTRYKL 
    KVEGYSGTA GDSMAYHNG RSFSTFDKD 
    TDSAITNCA LSYKGAFWY RNCHRVNLM 
    GRYGDNNHS QGVNWFHWK GHEHSIQFA 
    EMKLRPSNF RNLEGRRKR A
    UniProt P24821

    HT-5, tenascin splice isoform 2

    Sequence
    MGAMTQLLA GVFLAFLAL ATEGGVLKK 
    VIRHKRQSG VNATLPEEN QPVVFNHVY 
    NIKLPVGSQ CSVDLESAS GEKDLAPPS 
    EPSESFQEH TVDGENQIV FTHRINIPR 
    RACGCAAAP DVKELLSRL EELENLVSS 
    LREQCTAGA GCCLQPATG RLDTRPFCS 
    GRGNFSTEG CGCVCEPGW KGPNCSEPE 
    CPGNCHLRG RCIDGQCIC DDGFTGEDC 
    SQLACPSDC NDQGKCVNG VCICFEGYA 
    GADCSREIC PVPCSEEHG TCVDGLCVC 
    HDGFAGDDC NKPLCLNNC YNRGRCVEN 
    ECVCDEGFT GEDCSELIC PNDCFDRGR 
    CINGTCYCE EGFTGEDCG KPTCPHACH 
    TQGRCEEGQ CVCDEGFAG LDCSEKRCP 
    ADCHNRGRC VDGRCECDD GFTGADCGE 
    LKCPNGCSG HGRCVNGQC VCDEGYTGE 
    DCSQLRCPN DCHSRGRCV EGKCVCEQG 
    FKGYDCSDM SCPNDCHQH GRCVNGMCV 
    CDDGYTGED CRDRQCPRD CSNRGLCVD 
    GQCVCEDGF TGPDCAELS CPNDCHGQG 
    RCVNGQCVC HEGFMGKDC KEQRCPSDC 
    HGQGRCVDG QCICHEGFT GLDCGQHSC 
    PSDCNNLGQ CVSGRCICN EGYSGEDCS 
    EVSPPKDLV VTEVTEETV NLAWDNEMR 
    VTEYLVVYT PTHEGGLEM QFRVPGDQT 
    STIIQELEP GVEYFIRVF AILENKKSI 
    PVSARVATY LPAPEGLKF KSIKETSVE 
    VEWDPLDIA FETWEIIFR NMNKEDEGE 
    ITKSLRRPE TSYRQTGLA PGQEYEISL 
    HIVKNNTRG PGLKRVTTT RLDAPSQIE 
    VKDVTDTTA LITWFKPLA EIDGIELTY 
    GIKDVPGDR TTIDLTEDE NQYSIGNLK 
    PDTEYEVSL ISRRGDMSS NPAKETFTT 
    GLDAPRNLR RVSQTDNSI TLEWRNGKA 
    AIDSYRIKY APISGGDHA EVDVPKSQQ 
    ATTKTTLTG LRPGTEYGI GVSAVKEDK 
    ESNPATINA ATELDTPKD LQVSETAET 
    SLTLLWKTP LAKFDRYRL NYSLPTGQW 
    VGVQLPRNT TSYVLRGLE PGQEYNVLL 
    TAEKGRHKS KPARVKAST AKEPEIGNL 
    NVSDITPES FNLSWMATD GIFETFTIE 
    IIDSNRLLE TVEYNISGA ERTAHISGL 
    PPSTDFIVY LSGLAPSIR TKTISATAT 
    TEAEPEVDN LLVSDATPD GFRLSWTAD 
    EGVFDNFVL KIRDTKKQS EPLEITLLA 
    PERTRDLTG LREATEYEI ELYGISKGR 
    RSQTVSAIA TTAMGSPKE VIFSDITEN 
    SATVSWRAP TAQVESFRI TYVPITGGT 
    PSMVTVDGT KTQTRLVKL IPGVEYLVS 
    IIAMKGFEE SEPVSGSFT TALDGPSGL 
    VTANITDSE ALARWQPAI ATVDSYVIS 
    YTGEKVPEI TRTVSGNTV EYALTDLEP 
    ATEYTLRIF AEKGPQKSS TITAKFTTD 
    LDSPRDLTA TEVQSETAL LTWRPPRAS 
    VTGYLLVYE SVDGTVKEV IVGPDTTSY 
    SLADLSPST HYTAKIQAL NGPLRSNMI 
    QTIFTTIGL LYPFPKDCS QAMLNGDTT 
    SGLYTIYLN GDKAQALEV FCDMTSDGG 
    GWIVFLRRK NGRENFYQN WKAYAAGFG 
    DRREEFWLG LDNLNKITA QGQYELRVD 
    LRDHGETAF AVYDKFSVG DAKTRYKLK 
    VEGYSGTAG DSMAYHNGR SFSTFDKDT 
    DSAITNCAL SYKGAFWYR NCHRVNLMG 
    RYGDNNHSQ GVNWFHWKG HEHSIQFAE 
    MKLRPSNFR NLEGRRKRA
    UniProt P24821-2

    Tenascin splice isoform 3

    Sequence
    MGAMTQLLA GVFLAFLAL ATEGGVLKK 
    VIRHKRQSG VNATLPEEN QPVVFNHVY 
    NIKLPVGSQ CSVDLESAS GEKDLAPPS 
    EPSESFQEH TVDGENQIV FTHRINIPR 
    RACGCAAAP DVKELLSRL EELENLVSS 
    LREQCTAGA GCCLQPATG RLDTRPFCS 
    GRGNFSTEG CGCVCEPGW KGPNCSEPE 
    CPGNCHLRG RCIDGQCIC DDGFTGEDC 
    SQLACPSDC NDQGKCVNG VCICFEGYA 
    GADCSREIC PVPCSEEHG TCVDGLCVC 
    HDGFAGDDC NKPLCLNNC YNRGRCVEN 
    ECVCDEGFT GEDCSELIC PNDCFDRGR 
    CINGTCYCE EGFTGEDCG KPTCPHACH 
    TQGRCEEGQ CVCDEGFAG LDCSEKRCP 
    ADCHNRGRC VDGRCECDD GFTGADCGE 
    LKCPNGCSG HGRCVNGQC VCDEGYTGE 
    DCSQLRCPN DCHSRGRCV EGKCVCEQG 
    FKGYDCSDM SCPNDCHQH GRCVNGMCV 
    CDDGYTGED CRDRQCPRD CSNRGLCVD 
    GQCVCEDGF TGPDCAELS CPNDCHGQG 
    RCVNGQCVC HEGFMGKDC KEQRCPSDC 
    HGQGRCVDG QCICHEGFT GLDCGQHSC 
    PSDCNNLGQ CVSGRCICN EGYSGEDCS 
    EVSPPKDLV VTEVTEETV NLAWDNEMR 
    VTEYLVVYT PTHEGGLEM QFRVPGDQT 
    STIIQELEP GVEYFIRVF AILENKKSI 
    PVSARVATY LPAPEGLKF KSIKETSVE 
    VEWDPLDIA FETWEIIFR NMNKEDEGE 
    ITKSLRRPE TSYRQTGLA PGQEYEISL 
    HIVKNNTRG PGLKRVTTT RLDAPSQIE 
    VKDVTDTTA LITWFKPLA EIDGIELTY 
    GIKDVPGDR TTIDLTEDE NQYSIGNLK 
    PDTEYEVSL ISRRGDMSS NPAKETFTT 
    GLDAPRNLR RVSQTDNSI TLEWRNGKA 
    AIDSYRIKY APISGGDHA EVDVPKSQQ 
    ATTKTTLTG LRPGTEYGI GVSAVKEDK 
    ESNPATINA ATELDTPKD LQVSETAET 
    SLTLLWKTP LAKFDRYRL NYSLPTGQW 
    VGVQLPRNT TSYVLRGLE PGQEYNVLL 
    TAEKGRHKS KPARVKAST AKEPEIGNL 
    NVSDITPES FNLSWMATD GIFETFTIE 
    IIDSNRLLE TVEYNISGA ERTAHISGL 
    PPSTDFIVY LSGLAPSIR TKTISATAT 
    TEALPLLEN LTISDINPY GFTVSWMAS 
    ENAFDSFLV TVVDSGKLL DPQEFTLSG 
    TQRKLELRG LITGIGYEV MVSGFTQGH 
    QTKPLRAEI VTEAEPEVD NLLVSDATP 
    DGFRLSWTA DEGVFDNFV LKIRDTKKQ 
    SEPLEITLL APERTRDLT GLREATEYE 
    IELYGISKG RRSQTVSAI ATTAMGSPK 
    EVIFSDITE NSATVSWRA PTAQVESFR 
    ITYVPITGG TPSMVTVDG TKTQTRLVK 
    LIPGVEYLV SIIAMKGFE ESEPVSGSF 
    TTALDGPSG LVTANITDS EALARWQPA 
    IATVDSYVI SYTGEKVPE ITRTVSGNT 
    VEYALTDLE PATEYTLRI FAEKGPQKS 
    STITAKFTT DLDSPRDLT ATEVQSETA 
    LLTWRPPRA SVTGYLLVY ESVDGTVKE 
    VIVGPDTTS YSLADLSPS THYTAKIQA 
    LNGPLRSNM IQTIFTTIG LLYPFPKDC 
    SQAMLNGDT TSGLYTIYL NGDKAQALE 
    VFCDMTSDG GGWIVFLRR KNGRENFYQ 
    NWKAYAAGF GDRREEFWL GLDNLNKIT 
    AQGQYELRV DLRDHGETA FAVYDKFSV 
    GDAKTRYKL KVEGYSGTA GDSMAYHNG 
    RSFSTFDKD TDSAITNCA LSYKGAFWY 
    RNCHRVNLM GRYGDNNHS QGVNWFHWK 
    GHEHSIQFA EMKLRPSNF RNLEGRRKR 
    A
    UniProt P24821-3

    HT-33, tenascin splice isoform 4

    Sequence
    MGAMTQLLA GVFLAFLAL ATEGGVLKK 
    VIRHKRQSG VNATLPEEN QPVVFNHVY 
    NIKLPVGSQ CSVDLESAS GEKDLAPPS 
    EPSESFQEH TVDGENQIV FTHRINIPR 
    RACGCAAAP DVKELLSRL EELENLVSS 
    LREQCTAGA GCCLQPATG RLDTRPFCS 
    GRGNFSTEG CGCVCEPGW KGPNCSEPE 
    CPGNCHLRG RCIDGQCIC DDGFTGEDC 
    SQLACPSDC NDQGKCVNG VCICFEGYA 
    GADCSREIC PVPCSEEHG TCVDGLCVC 
    HDGFAGDDC NKPLCLNNC YNRGRCVEN 
    ECVCDEGFT GEDCSELIC PNDCFDRGR 
    CINGTCYCE EGFTGEDCG KPTCPHACH 
    TQGRCEEGQ CVCDEGFAG LDCSEKRCP 
    ADCHNRGRC VDGRCECDD GFTGADCGE 
    LKCPNGCSG HGRCVNGQC VCDEGYTGE 
    DCSQLRCPN DCHSRGRCV EGKCVCEQG 
    FKGYDCSDM SCPNDCHQH GRCVNGMCV 
    CDDGYTGED CRDRQCPRD CSNRGLCVD 
    GQCVCEDGF TGPDCAELS CPNDCHGQG 
    RCVNGQCVC HEGFMGKDC KEQRCPSDC 
    HGQGRCVDG QCICHEGFT GLDCGQHSC 
    PSDCNNLGQ CVSGRCICN EGYSGEDCS 
    EVSPPKDLV VTEVTEETV NLAWDNEMR 
    VTEYLVVYT PTHEGGLEM QFRVPGDQT 
    STIIQELEP GVEYFIRVF AILENKKSI 
    PVSARVATY LPAPEGLKF KSIKETSVE 
    VEWDPLDIA FETWEIIFR NMNKEDEGE 
    ITKSLRRPE TSYRQTGLA PGQEYEISL 
    HIVKNNTRG PGLKRVTTT RLDAPSQIE 
    VKDVTDTTA LITWFKPLA EIDGIELTY 
    GIKDVPGDR TTIDLTEDE NQYSIGNLK 
    PDTEYEVSL ISRRGDMSS NPAKETFTT 
    GLDAPRNLR RVSQTDNSI TLEWRNGKA 
    AIDSYRIKY APISGGDHA EVDVPKSQQ 
    ATTKTTLTG LRPGTEYGI GVSAVKEDK 
    ESNPATINA ATELDTPKD LQVSETAET 
    SLTLLWKTP LAKFDRYRL NYSLPTGQW 
    VGVQLPRNT TSYVLRGLE PGQEYNVLL 
    TAEKGRHKS KPARVKAST EQAPELENL 
    TVTEVGWDG LRLNWTAAD QAYEHFIIQ 
    VQEANKVEA ARNLTVPGS LRAVDIPGL 
    KAATPYTVS IYGVIQGYR TPVLSAEAS 
    TGETPNLGE VVVAEVGWD ALKLNWTAP 
    EGAYEYFFI QVQEADTVE AAQNLTVPG 
    GLRSTDLPG LKAATHYTI TIRGVTQDF 
    STTPLSVEV LTEEVPDMG NLTVTEVSW 
    DALRLNWTT PDGTYDQFT IQVQEADQV 
    EEAHNLTVP GSLRSMEIP GLRAGTPYT 
    VTLHGEVRG HSTRPLAVE VVTEDLPQL 
    GDLAVSEVG WDGLRLNWT AADNAYEHF 
    VIQVQEVNK VEAAQNLTL PGSLRAVDI 
    PGLEAATPY RVSIYGVIR GYRTPVLSA 
    EASTAKEPE IGNLNVSDI TPESFNLSW 
    MATDGIFET FTIEIIDSN RLLETVEYN 
    ISGAERTAH ISGLPPSTD FIVYLSGLA 
    PSIRTKTIS ATATTEAEP EVDNLLVSD 
    ATPDGFRLS WTADEGVFD NFVLKIRDT 
    KKQSEPLEI TLLAPERTR DLTGLREAT 
    EYEIELYGI SKGRRSQTV SAIATTAMG 
    SPKEVIFSD ITENSATVS WRAPTAQVE 
    SFRITYVPI TGGTPSMVT VDGTKTQTR 
    LVKLIPGVE YLVSIIAMK GFEESEPVS 
    GSFTTALDG PSGLVTANI TDSEALARW 
    QPAIATVDS YVISYTGEK VPEITRTVS 
    GNTVEYALT DLEPATEYT LRIFAEKGP 
    QKSSTITAK FTTDLDSPR DLTATEVQS 
    ETALLTWRP PRASVTGYL LVYESVDGT 
    VKEVIVGPD TTSYSLADL SPSTHYTAK 
    IQALNGPLR SNMIQTIFT TIGLLYPFP 
    KDCSQAMLN GDTTSGLYT IYLNGDKAQ 
    ALEVFCDMT SDGGGWIVF LRRKNGREN 
    FYQNWKAYA AGFGDRREE FWLGLDNLN 
    KITAQGQYE LRVDLRDHG ETAFAVYDK 
    FSVGDAKTR YKLKVEGYS GTAGDSMAY 
    HNGRSFSTF DKDTDSAIT NCALSYKGA 
    FWYRNCHRV NLMGRYGDN NHSQGVNWF 
    HWKGHEHSI QFAEMKLRP SNFRNLEGR 
    RKRA
    UniProt P24821-4

    Tenascin splice isoform 5

    Sequence
    MGAMTQLLA GVFLAFLAL ATEGGVLKK 
    VIRHKRQSG VNATLPEEN QPVVFNHVY 
    NIKLPVGSQ CSVDLESAS GEKDLAPPS 
    EPSESFQEH TVDGENQIV FTHRINIPR 
    RACGCAAAP DVKELLSRL EELENLVSS 
    LREQCTAGA GCCLQPATG RLDTRPFCS 
    GRGNFSTEG CGCVCEPGW KGPNCSEPE 
    CPGNCHLRG RCIDGQCIC DDGFTGEDC 
    SQLACPSDC NDQGKCVNG VCICFEGYA 
    GADCSREIC PVPCSEEHG TCVDGLCVC 
    HDGFAGDDC NKPLCLNNC YNRGRCVEN 
    ECVCDEGFT GEDCSELIC PNDCFDRGR 
    CINGTCYCE EGFTGEDCG KPTCPHACH 
    TQGRCEEGQ CVCDEGFAG LDCSEKRCP 
    ADCHNRGRC VDGRCECDD GFTGADCGE 
    LKCPNGCSG HGRCVNGQC VCDEGYTGE 
    DCSQLRCPN DCHSRGRCV EGKCVCEQG 
    FKGYDCSDM SCPNDCHQH GRCVNGMCV 
    CDDGYTGED CRDRQCPRD CSNRGLCVD 
    GQCVCEDGF TGPDCAELS CPNDCHGQG 
    RCVNGQCVC HEGFMGKDC KEQRCPSDC 
    HGQGRCVDG QCICHEGFT GLDCGQHSC 
    PSDCNNLGQ CVSGRCICN EGYSGEDCS 
    EVSPPKDLV VTEVTEETV NLAWDNEMR 
    VTEYLVVYT PTHEGGLEM QFRVPGDQT 
    STIIQELEP GVEYFIRVF AILENKKSI 
    PVSARVATY LPAPEGLKF KSIKETSVE 
    VEWDPLDIA FETWEIIFR NMNKEDEGE 
    ITKSLRRPE TSYRQTGLA PGQEYEISL 
    HIVKNNTRG PGLKRVTTT RLDAPSQIE 
    VKDVTDTTA LITWFKPLA EIDGIELTY 
    GIKDVPGDR TTIDLTEDE NQYSIGNLK 
    PDTEYEVSL ISRRGDMSS NPAKETFTT 
    GLDAPRNLR RVSQTDNSI TLEWRNGKA 
    AIDSYRIKY APISGGDHA EVDVPKSQQ 
    ATTKTTLTG LRPGTEYGI GVSAVKEDK 
    ESNPATINA ATELDTPKD LQVSETAET 
    SLTLLWKTP LAKFDRYRL NYSLPTGQW 
    VGVQLPRNT TSYVLRGLE PGQEYNVLL 
    TAEKGRHKS KPARVKAST EAEPEVDNL 
    LVSDATPDG FRLSWTADE GVFDNFVLK 
    IRDTKKQSE PLEITLLAP ERTRDLTGL 
    REATEYEIE LYGISKGRR SQTVSAIAT 
    TAMGSPKEV IFSDITENS ATVSWRAPT 
    AQVESFRIT YVPITGGTP SMVTVDGTK 
    TQTRLVKLI PGVEYLVSI IAMKGFEES 
    EPVSGSFTT ALDGPSGLV TANITDSEA 
    LARWQPAIA TVDSYVISY TGEKVPEIT 
    RTVSGNTVE YALTDLEPA TEYTLRIFA 
    EKGPQKSST ITAKFTTDL DSPRDLTAT 
    EVQSETALL TWRPPRASV TGYLLVYES 
    VDGTVKEVI VGPDTTSYS LADLSPSTH 
    YTAKIQALN GPLRSNMIQ TIFTTIGLL 
    YPFPKDCSQ AMLNGDTTS GLYTIYLNG 
    DKAQALEVF CDMTSDGGG WIVFLRRKN 
    GRENFYQNW KAYAAGFGD RREEFWLGL 
    DNLNKITAQ GQYELRVDL RDHGETAFA 
    VYDKFSVGD AKTRYKLKV EGYSGTAGD 
    SMAYHNGRS FSTFDKDTD SAITNCALS 
    YKGAFWYRN CHRVNLMGR YGDNNHSQG 
    VNWFHWKGH EHSIQFAEM KLRPSNFRN 
    LEGRRKRA
    UniProt P24821-5

    P31, tenascin splice isoform 6

    Sequence
    MGAMTQLLA GVFLAFLAL ATEGGVLKK 
    VIRHKRQSG VNATLPEEN QPVVFNHVY 
    NIKLPVGSQ CSVDLESAS GEKDLAPPS 
    EPSESFQEH TVDGENQIV FTHRINIPR 
    RACGCAAAP DVKELLSRL EELENLVSS 
    LREQCTAGA GCCLQPATG RLDTRPFCS 
    GRGNFSTEG CGCVCEPGW KGPNCSEPE 
    CPGNCHLRG RCIDGQCIC DDGFTGEDC 
    SQLACPSDC NDQGKCVNG VCICFEGYA 
    GADCSREIC PVPCSEEHG TCVDGLCVC 
    HDGFAGDDC NKPLCLNNC YNRGRCVEN 
    ECVCDEGFT GEDCSELIC PNDCFDRGR 
    CINGTCYCE EGFTGEDCG KPTCPHACH 
    TQGRCEEGQ CVCDEGFAG LDCSEKRCP 
    ADCHNRGRC VDGRCECDD GFTGADCGE 
    LKCPNGCSG HGRCVNGQC VCDEGYTGE 
    DCSQLRCPN DCHSRGRCV EGKCVCEQG 
    FKGYDCSDM SCPNDCHQH GRCVNGMCV 
    CDDGYTGED CRDRQCPRD CSNRGLCVD 
    GQCVCEDGF TGPDCAELS CPNDCHGQG 
    RCVNGQCVC HEGFMGKDC KEQRCPSDC 
    HGQGRCVDG QCICHEGFT GLDCGQHSC 
    PSDCNNLGQ CVSGRCICN EGYSGEDCS 
    EVSPPKDLV VTEVTEETV NLAWDNEMR 
    VTEYLVVYT PTHEGGLEM QFRVPGDQT 
    STIIQELEP GVEYFIRVF AILENKKSI 
    PVSARVATY LPAPEGLKF KSIKETSVE 
    VEWDPLDIA FETWEIIFR NMNKEDEGE 
    ITKSLRRPE TSYRQTGLA PGQEYEISL 
    HIVKNNTRG PGLKRVTTT RLDAPSQIE 
    VKDVTDTTA LITWFKPLA EIDGIELTY 
    GIKDVPGDR TTIDLTEDE NQYSIGNLK 
    PDTEYEVSL ISRRGDMSS NPAKETFTT 
    GLDAPRNLR RVSQTDNSI TLEWRNGKA 
    AIDSYRIKY APISGGDHA EVDVPKSQQ 
    ATTKTTLTG LRPGTEYGI GVSAVKEDK 
    ESNPATINA ATELDTPKD LQVSETAET 
    SLTLLWKTP LAKFDRYRL NYSLPTGQW 
    VGVQLPRNT TSYVLRGLE PGQEYNVLL 
    TAEKGRHKS KPARVKAST AMGSPKEVI 
    FSDITENSA TVSWRAPTA QVESFRITY 
    VPITGGTPS MVTVDGTKT QTRLVKLIP 
    GVEYLVSII AMKGFEESE PVSGSFTTA 
    LDGPSGLVT ANITDSEAL ARWQPAIAT 
    VDSYVISYT GEKVPEITR TVSGNTVEY 
    ALTDLEPAT EYTLRIFAE KGPQKSSTI 
    TAKFTTDLD SPRDLTATE VQSETALLT 
    WRPPRASVT GYLLVYESV DGTVKEVIV 
    GPDTTSYSL ADLSPSTHY TAKIQALNG 
    PLRSNMIQT IFTTIGLLY PFPKDCSQA 
    MLNGDTTSG LYTIYLNGD KAQALEVFC 
    DMTSDGGGW IVFLRRKNG RENFYQNWK 
    AYAAGFGDR REEFWLGLD NLNKITAQG 
    QYELRVDLR DHGETAFAV YDKFSVGDA 
    KTRYKLKVE GYSGTAGDS MAYHNGRSF 
    STFDKDTDS AITNCALSY KGAFWYRNC 
    HRVNLMGRY GDNNHSQGV NWFHWKGHE 
    HSIQFAEMK LRPSNFRNL EGRRKRA
    UniProt P24821-6

    Links to other resources

    UniProt P24821
    Ensembl ENST00000350763
    KEGG hsa:3371
    • Anatomical structure: cartilage

    • Anatomical structure: macrophage

    • Anatomical structure: fibroblast

    Targets

    Reference